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Steven Pierre Grant, Age 5537 Belfort Loop, Newark, DE 19702

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Known as:
Steven P Grant Steven D Grant Steven O Grant Stephen P Grant Steve P Grant
Related to:
Omar Grant

Steven Grant Phones & Addresses

Newark, DE

Richmond, VA

1971 Grand Ave, Bronx, NY 10453 (718) 583-0042 (718) 583-5832

Owings Mills, MD

Mount Vernon, NY

Jamaica, NY

Work

Company: Virginia Commonwealth University INT Address: 1250 E Marshall St, Richmond, VA 23298 Phones: (800) 762-6161 (Phone)

Education

School / High School: Mount Sinai School Of Medicine Of New York University 1973

Languages

English • Spanish

Awards

Healthgrades Honor Roll

Ranks

Certificate: Hematology, 1978

Mentions for Steven Pierre Grant

Career records & work history

Real Estate Brokers

Steven Grant Photo 1

Steven Grant

Specialties:
Buyer's Agent, Listing Agent
Work:
steven pro
65 Ave Str
(914) 620-2761 (Office)

Lawyers & Attorneys

Steven Grant Photo 2

Steven A. Grant, New York NY - Lawyer

Address:
9Th Floor 305 Broadway, New York, NY 10007
Specialties:
Bankruptcy, Business Law, Consumer Law
Jurisdiction:
Texas
Memberships:
Texas State Bar
Steven Grant Photo 3

Steven A. Grant, New York NY - Lawyer

Address:
305 Broadway Fl 7Th, New York, NY 10007
(212) 822-1451 (Office)
Licenses:
New York - Due to reregister within 30 days of birthday 2003
Steven Grant Photo 4

Steven Paul Grant, Dobbs Ferry NY - Lawyer

Address:
Grant & Longworth, LLP
377 Ashford Ave, Dobbs Ferry, NY 10522
(914) 479-5804 (Office)
Licenses:
New York - Currently registered 1984
Education:
Benjamin N Cardozo
Steven Grant Photo 5

Steven Grant - Lawyer

Office:
The Florida Law Office
Specialties:
Asset Protection, Business Law, Civil Practice, Collections, Consumer Collections, Consumer Credit, Consumer Credit Compliance, Consumer Finance, Consumer Fraud, Consumer Litigation, Consumer Protection, Consumer Rights, Contracts, Cybersquatting, Debtor and Creditor, Divorce, Fair Credit Reporting Act, Fraud and Deceit, General Practice, International Law, International Trade, Minimum Wage Law, Personal Injury, Probate Law, Property Law, Real Property, Torts, Estate Planning, Trusts and Estates, Lawsuits & Disputes, Unfair Competition, Wills, City, County & Local Govt Law
ISLN:
921624415
Admitted:
2010
University:
University of Maryland, B.S., 2005
Law School:
Florida Coastal School of Law, J.D., 2010
Steven Grant Photo 6

Steven Grant - Lawyer

Office:
Grant & Longworth
Specialties:
Tort Law, Negligence Law
ISLN:
906931248
Admitted:
1984
University:
New York University, B.A., 1980
Law School:
Benjamin N. Cardozo School of Law, J.D., 1983
Steven Grant Photo 7

Steven Grant - Lawyer

Office:
Law Offices of Steven A. Grant
Specialties:
Litigation, Criminal Defense, Contracts & Agreements, Employment & Labor, Criminal Defense, Consumer Bankruptcy, Landlord and Tenant Law, Consumer Rights, Consumer Law, Bankruptcy
ISLN:
917538108
Admitted:
2002
University:
State University of New York at Stony Brook, B.A., 1980
Law School:
Fordham University Law School, J.D., 2002
Steven Grant Photo 8

Steven Grant - Lawyer

Office:
Law Office of Steven A. Grant
Specialties:
Lawsuits & Disputes, Criminal Defense, Litigation, Real Estate, Landlord and Tenant Law, Contracts, Employment Disputes
ISLN:
918301572
Admitted:
2004
University:
University of Massachusetts, B.A., 1998
Law School:
Suffolk University Law School, J.D., 2003
Steven Grant Photo 9

Steven P. Grant, Bronx NY - Lawyer

Office:
Grant & Longworth
2435 Eastchester Rd., Bronx, NY
Specialties:
Tort Law, Negligence Law
ISLN:
906931248
Admitted:
1984
University:
New York University, B.A.
Law School:
Benjamin N. Cardozo School of Law, Yeshiva University, J.D.

Medicine Doctors

Steven Grant Photo 10

Dr. Steven Grant, Richmond VA - MD (Doctor of Medicine)

Specialties:
Hematology
Medical Oncology
Oncology
Address:
Virginia Commonwealth University INT
1250 E Marshall St, Richmond, VA 23298
(800) 762-6161 (Phone)
1300 E Marshall St, Richmond, VA 23298
(804) 828-9992 (Phone)
Certifications:
Hematology, 1978
Internal Medicine, 1976
Medical Oncology, 1979
Awards:
Healthgrades Honor Roll
Languages:
English
Spanish
Hospitals:
Virginia Commonwealth University INT
1250 E Marshall St, Richmond, VA 23298
1300 E Marshall St, Richmond, VA 23298
Education:
Medical School
Mount Sinai School Of Medicine Of New York University
Graduated: 1973
Medical School
Mt Sinai Hospital
Graduated: 1974
Medical School
Mt Sinai Hospital
Graduated: 1976
Medical School
Mt Sinai Hospital
Graduated: 1978
Medical School
Yale University Hospital
Graduated: 1979

Steven A. Grant

Specialties:
Family Medicine
Work:
Providence Medical GroupProvidence Physicians Group
1830 Bickford Ave STE 211, Snohomish, WA 98290
(360) 563-5900 (phone) (360) 563-5905 (fax)
Site
Education:
Medical School
University of North Texas College of Osteopathic Medicine
Graduated: 2003
Procedures:
Wound Care, Arthrocentesis, Destruction of Benign/Premalignant Skin Lesions, Electrocardiogram (EKG or ECG), Psychological and Neuropsychological Tests, Skin Tags Removal, Vaccine Administration
Conditions:
Acne, Acute Bronchitis, Acute Sinusitis, Allergic Rhinitis, Anemia, Anxiety Phobic Disorders, Attention Deficit Disorder (ADD), Bipolar Disorder, Carpel Tunnel Syndrome, Chronic Renal Disease, Chronic Sinusitis, Constipation, Contact Dermatitis, Gastroesophageal Reflux Disease (GERD), Infectious Liver Disease, Intervertebral Disc Degeneration, Migraine Headache, Otitis Media, Overweight and Obesity, Peripheral Nerve Disorders, Plantar Warts, Pneumonia, Sciatica, Substance Abuse and/or Dependency, Abdominal Aortic Aneurysm, Abdominal Hernia, Abnormal Vaginal Bleeding, Acute Otitis Externa, Acute Pancreatitis, Acute Pharyngitis, Acute Renal Failure, Acute Upper Respiratory Tract Infections, Alcohol Dependence, Alopecia Areata, Alzheimer's Disease, Anxiety Dissociative and Somatoform Disorders, Atopic Dermatitis, Atrial Fibrillation and Atrial Flutter, Autism, Bacterial Pneumonia, Benign Neoplasm of Breast, Benign Paroxysmal Positional Vertigo, Benign Prostatic Hypertrophy, Benign Thyroid Diseases, Breast Disorders, Bronchial Asthma, Burns, Calculus of the Urinary System, Candidiasis, Candidiasis of Vulva and Vagina, Cardiac Arrhythmia, Cataract, Cholelethiasis or Cholecystitis, Chronic Bronchitis, Cirrhosis, Conduction Disorders, Croup, Dementia, Depressive Disorders, Dermatitis, Deviated Nasal Septum, Diabetes Mellitus (DM), Diabetic Peripheral Neuropathy, Disorders of Lipoid Metabolism, Diverticulitis, Diverticulosis, Eating Disorders, Epilepsy, Erectile Dysfunction (ED), Esophagitis, Female Infertility, Fractures, Dislocations, Derangement, and Sprains, Gastrointestinal Hemorrhage, Genital HPV, Gingival and Periodontal Diseases, Glaucoma, Gout, Hallux Valgus, Hearing Loss, Heart Failure, Hemorrhoids, Herpes Genitalis, Herpes Simplex, Herpes Zoster, Hypertension (HTN), Hyperthyroidism, Hypothyroidism, Inflammatory Bowel Disease (IBD), Inguinal Hernia, Insomnia, Internal Derangement of Knee, Internal Derangement of Knee Cartilage, Intestinal Obstruction, Intracranial Injury, Iron Deficiency Anemia, Irritable Bowel Syndrome (IBS), Ischemic Bowel Disease, Ischemic Stroke, Lateral Epicondylitis, Menopausal and Postmenopausal Disorders, Metabolic Syndrome, Non-Toxic Goiter, Obsessive-Compulsive Disorder (OCD), Obstructive Sleep Apnea, Osteoarthritis, Peptic Ulcer Disease, Phlebitis and Thrombophlebitis, Plantar Fascitis, Poisoning by Drugs, Meds, or Biological Substances, Post Traumatic Stress Disorder (PTSD), Premenstrual Syndrome (PMS), Prostatitis, Psoriasis, Restless Leg Syndrome, Rheumatoid Arthritis, Rosacea, Rotator Cuff Syndrome and Allied Disorders, Schizophrenia, Scoliosis or Kyphoscoliosis, Sexually Transmitted Diseases (STDs), Skin and Subcutaneous Infections, Spinal Stenosis, Systemic Lupus Erythematosus, Tempromandibular Joint Disorders (TMJ), Tension Headache, Thyroiditis, Tinea Pedis, Tinea Unguium, Transient Cerebral Ischemia, Urinary Incontinence, Urinary Tract Infection (UT), Varicose Veins, Venous Embolism and Thrombosis, Ventral Hernia, Vitamin D Deficiency
Languages:
English, Spanish
Description:
Dr. Grant graduated from the University of North Texas College of Osteopathic Medicine in 2003. He works in Snohomish, WA and specializes in Family Medicine. Dr. Grant is affiliated with Providence Regional Medical Center Everett and Swedish Medical Center - First Hill.

Steven W. Grant

Specialties:
General Surgery
Work:
Associates In General Surgery
3610 Long Bch Blvd STE 101, Long Beach, CA 90807
(562) 424-0421 (phone) (562) 427-8005 (fax)
Site
Education:
Medical School
Thomas Jefferson University, Jefferson Medical College
Graduated: 1993
Procedures:
Breast Reconstruction, Hernia Repair, Laparoscopic Gallbladder Removal, Mastectomy, Small Bowel Resection
Conditions:
Abdominal Hernia, Appendicitis, Cholelethiasis or Cholecystitis, Hemorrhoids, Inguinal Hernia, Intestinal Obstruction, Malignant Neoplasm of Colon, Ventral Hernia, Breast Disorders, Femoral Hernia, Gastric Cancer, Gastrointestinal Hemorrhage, Intussusception, Ischemic Bowel Disease, Liver Cancer, Malignant Neoplasm of Esophagus, Malignant Neoplasm of Female Breast, Melanoma, Pancreatic Cancer, Rectal, Abdomen, Small Intestines, or Colon Cancer, Skin Cancer
Languages:
English, Spanish
Description:
Dr. Grant graduated from the Thomas Jefferson University, Jefferson Medical College in 1993. He works in Long Beach, CA and specializes in General Surgery. Dr. Grant is affiliated with Long Beach Memorial Medical Center.

Steven R. Grant

Specialties:
Hematology/Oncology, Hospice & Palliative Medicine
Work:
Massey Cancer Center
1300 E Marshall St, Richmond, VA 23298
(804) 828-9992 (phone) (804) 828-5941 (fax)
Education:
Medical School
Mount Sinai School of Medicine
Graduated: 1973
Procedures:
Bone Marrow Biopsy
Conditions:
Anxiety Phobic Disorders, Hypertension (HTN), Malignant Neoplasm of Female Breast, Multiple Myeloma
Languages:
English
Description:
Dr. Grant graduated from the Mount Sinai School of Medicine in 1973. He works in Richmond, VA and specializes in Hematology/Oncology and Hospice & Palliative Medicine. Dr. Grant is affiliated with Virginia Commonwealth University Medical Center.

Steven M. Grant

Specialties:
Internal Medicine
Work:
University Of Vermont Medical Center
111 Colchester Ave, Burlington, VT 05401
(802) 847-4237 (phone) (802) 847-5784 (fax)
Internal Medicine Hospitalist Service
111 Colchester Ave Main Campus Baird 798, Burlington, VT 05401
(802) 847-7911 (phone) (802) 847-5784 (fax)
Education:
Medical School
Emory University School of Medicine
Graduated: 1993
Procedures:
Arthrocentesis
Conditions:
Acute Renal Failure, Atrial Fibrillation and Atrial Flutter, Heart Failure, Pneumonia, Acute Pancreatitis, Alzheimer's Disease, Anemia, Cardiac Arrhythmia, Chronic Bronchitis, Chronic Renal Disease, Diabetes Mellitus (DM), Fractures, Dislocations, Derangement, and Sprains, Gastrointestinal Hemorrhage, Gout, Hypertension (HTN), Intervertebral Disc Degeneration, Obstructive Sleep Apnea, Osteomyelitis, Pulmonary Embolism, Urinary Tract Infection (UT), Venous Embolism and Thrombosis
Languages:
English
Description:
Dr. Grant graduated from the Emory University School of Medicine in 1993. He works in Burlington, VT and 1 other location and specializes in Internal Medicine. Dr. Grant is affiliated with The University Of Vermont Medical Center.

Steven D. Grant

Specialties:
Internal Medicine
Work:
Doctors Of Internal Medicine
30335 W 13 Mile Rd STE 100, Farmington, MI 48334
(248) 626-6500 (phone) (248) 855-0190 (fax)
Education:
Medical School
University of Michigan Medical School
Graduated: 1976
Procedures:
Allergen Immunotherapy, Destruction of Benign/Premalignant Skin Lesions, Electrocardiogram (EKG or ECG), Hearing Evaluation, Pulmonary Function Tests, Skin Tags Removal, Vaccine Administration
Conditions:
Abdominal Hernia, Acne, Atrial Fibrillation and Atrial Flutter, Attention Deficit Disorder (ADD), Benign Prostatic Hypertrophy, Cardiac Arrhythmia, Chronic Fatigue Syndrome, Chronic Renal Disease, Constipation, Dermatitis, Erectile Dysfunction (ED), Esophagitis, Gastrointestinal Hemorrhage, Gout, Hearing Loss, Herpes Zoster, Hypertension (HTN), Hypothyroidism, Inguinal Hernia, Irritable Bowel Syndrome (IBS), Ischemic Heart Disease, Overweight and Obesity, Urinary Incontinence, Acute Bronchitis, Acute Myocardial Infarction (AMI), Acute Pharyngitis, Acute Sinusitis, Acute Upper Respiratory Tract Infections, Alopecia Areata, Anemia, Anxiety Phobic Disorders, Aortic Aneurism, Aortic Valvular Disease, Bell's Palsy, Benign Paroxysmal Positional Vertigo, Benign Polyps of the Colon, Benign Thyroid Diseases, Bronchial Asthma, Calculus of the Urinary System, Candidiasis, Cardiomyopathy, Carpel Tunnel Syndrome, Cataract, Celiac Disease, Cirrhosis, Congenital Anomalies of the Heart, Contact Dermatitis, Dementia, Diabetes Mellitus (DM), Disorders of Lipoid Metabolism, Diverticulitis, Epilepsy, Fractures, Dislocations, Derangement, and Sprains, Gastroesophageal Reflux Disease (GERD), Hallux Valgus, Heart Failure, Hemorrhoids, Herpes Simplex, Infectious Liver Disease, Inflammatory Bowel Disease (IBD), Lateral Epicondylitis, Macular Degeneration, Malignant Neoplasm of Female Breast, Melanoma, Menopausal and Postmenopausal Disorders, Metabolic Syndrome, Migraine Headache, Mitral Valvular Disease, Multiple Sclerosis (MS), Non-Toxic Goiter, Osteoarthritis, Osteoporosis, Otitis Media, Peripheral Nerve Disorders, Plantar Fascitis, Pneumonia, Prostatitis, Psoriasis, Restless Leg Syndrome, Rheumatoid Arthritis, Rosacea, Rotator Cuff Syndrome and Allied Disorders, Sarcoidosis, Skin and Subcutaneous Infections, Spinal Stenosis, Substance Abuse and/or Dependency, Tempromandibular Joint Disorders (TMJ), Transient Cerebral Ischemia, Urinary Tract Infection (UT), Valvular Heart Disease, Varicose Veins, Venous Embolism and Thrombosis, Vitamin D Deficiency
Languages:
English
Description:
Dr. Grant graduated from the University of Michigan Medical School in 1976. He works in Farmington Hills, MI and specializes in Internal Medicine.

Steven M. Grant

Specialties:
Podiatric Medicine
Work:
Steven M Grant DPM
485 Williamstown Rd, Sicklerville, NJ 08081
(856) 237-8080 (phone) (856) 237-8042 (fax)
Procedures:
Hallux Valgus Repair
Conditions:
Plantar Fascitis, Tinea Pedis
Languages:
English
Description:
Dr. Grant works in Sicklerville, NJ and specializes in Podiatric Medicine. Dr. Grant is affiliated with Kennedy University Hospital-Stratford, Virtua Berlin, Virtua Marlton Hospital and Virtua Voorhees Hospital.
Steven Grant Photo 11

Steven Grant, Richmond VA

Specialties:
Internal Medicine
Hematology
Medical Oncology
Hematology & Oncology
Work:
VCU Health System
1300 E Marshall St, Richmond, VA 23298VCU Health System
1101 E Marshall St, Richmond, VA 23298VCU Health System
1250 E Marshall St, Richmond, VA 23298VCU Health System
Medical College Of Virginia, Richmond, VA 23219
Education:
New York University - Mount Sinai (1973)

License Records

Steven Grant

Licenses:
License #: 23593 - Active
Issued Date: Jan 26, 2005
Renew Date: Dec 1, 2015
Expiration Date: Nov 30, 2017
Type: Certified Public Accountant

Steven Grant resumes & CV records

Resumes

Steven Grant Photo 45

Senior Geophysicist

Industry:
Environmental Services
Work:
Hager Group
Senior Geophysicist Natural Resources Canada Jan 1998 - Nov 1998
Technical Support University of Alberta Sep 1993 - Dec 1996
Research Assistant and Teaching Assistant
Education:
University of Alberta 1993 - 1997
Master of Science, Masters, Geology Dalhousie University 1989 - 1993
Steven Grant Photo 46

Professor Of Medicine

Location:
Richmond, VA
Industry:
Research
Work:
Viriginia Commonwealth University Health Sciences University
Professor of Medicine Vcu School of Medicine
Professor of Medicine
Skills:
Science, Molecular Biology, Clinical Research, Epidemiology, Cell Biology, Biochemistry, Cancer, Research, Immunology, Clinical Trials, Medical Education, Medicine, University Teaching, Cell Culture
Steven Grant Photo 47

Healt At Vcu Health System

Location:
1250 east Marshall St, Richmond, VA 23284
Industry:
Hospital & Health Care
Work:
VCU Health System
healt
Steven Grant Photo 48

Steven Grant

Steven Grant Photo 49

Steven Grant

Steven Grant Photo 50

Steven Grant

Steven Grant Photo 51

Senior Planner At Bowman Consulting Group

Position:
Member, Secretary to the Board at Prince William County Board of Equalization, Senior Planner at Bowman Consulting Group
Location:
Manassas, Virginia
Industry:
Architecture & Planning
Work:
Prince William County Board of Equalization - Prince William County Government Center since 2008
Member, Secretary to the Board Bowman Consulting Group - Chantilly and Manassas, Virginia since Jan 2004
Senior Planner Town of Hilton Head Island, SC May 1997 - Dec 2003
Senior Grants Administrator Town of Hilton Head Island, South Carolina Sep 1996 - Apr 1997
Planner
Education:
George Mason University 1989 - 1993
Bachelor of Science, Public Administration
Skills:
Land planner, Entitlements, Report Writing, Comprehensive Planning, Project Management, Land Use Planning, Urban Design, Site Plans, Feasibility Studies
Certifications:
Certified Planner, The American Institute of Certified Planners
Steven Grant Photo 52

Steven Grant

Location:
United States

Publications & IP owners

Us Patents

Combination Of Glivec (Sti571) With A Cyclin-Dependent Kinase Inhibitor, Especially Flavopiridol, In The Treatment Of Cancer

US Patent:
7888341, Feb 15, 2011
Filed:
Apr 4, 2003
Appl. No.:
10/510531
Inventors:
Paul Dent - GlenAllen VA, US
Steven Grant - Richmond VA, US
Geoffrey Krystal - Richmond VA, US
Chunrong Yu - Richmond VA, US
Assignee:
The United States of America as represented by the Department of Veterans Affairs - Washington DC
Virginia Commonwealth University - Richmond VA
International Classification:
A01N 43/58
A61K 31/50
US Classification:
514183, 514247
Abstract:
The present invention pertains to a combination for simultaneous, separate or sequential use which comprises (a) a cyclin-dependent kinase inhibitor and (b) 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide and to its use for the treatment of cancer, especially of Bcr/Abl leukemia resistant to compound of formula I.

Tumor Cell Killing By Cell Cycle Checkpoint Abrogation Combined With Inhibition Of The Classical Mitogen Activated Protein (Map) Kinase Pathway

US Patent:
2004019, Sep 30, 2004
Filed:
Nov 4, 2003
Appl. No.:
10/363993
Inventors:
Paul Dent - Glen Allen VA, US
Steven Grant - Richmond VA, US
Robert McKinstry - Richmond VA, US
Yun Dai - Richmond VA, US
Chunrong Yu - Richmond VA, US
International Classification:
A61K051/00
A61K031/522
US Classification:
424/001490, 514/263310, 514/453000
Abstract:
The present invention provides a method for treating cancer by promoting apoptosis and reducing clonogenic survival of cancer cells. The method encompasses co-administering 1) a cell cycle checkpoint abrogation agent (for example, UCN-01 or caffeine) and 2) an inhibitor of a compensatory cytoprotective pathway, such as an agent that inhibits the MEK 1/2 pathway (e.g. PD98059, U0126, or PD184352) or an agent that inhibits the PI 3 pathway (e.g. LIY294002 or wortmanin). In addition, because the co-administration step also radiosensitizes cancer cells, the method additionally encompasses the administration of radiation to further reduce clonogenic survival of cancer cells. The method promotes apoptosis and reduces clonogenic survival in many types of cancer cells, including leukemia cells, prostate cancer cells, breast cancer cells, myeloma cells, and lymphoma cells.

Promotion Of Adoptosis In Cancer Cells By Co-Administration Of Cyclin Dependent Kinase Inhibitiors And Cellular Differentiation Agents

US Patent:
2005000, Jan 6, 2005
Filed:
Sep 7, 2001
Appl. No.:
10/363540
Inventors:
Steven Grant - Richmond VA, US
Paul Dent - Glen Allen VA, US
Roberto Rosato - Richmond VA, US
Leanne Cartee - Atlanta GA, US
International Classification:
A61K038/12
A61K031/353
A61K031/19
US Classification:
514007000, 514009000, 514167000, 514460000, 514456000, 514559000, 514575000
Abstract:
The invention provides compositions and methods for promoting apoptosis of cancer cells, and methods for treating cancer. The compositions comprise cyclin dependent kinase inhibitor and an agent that induces cellular differentiation. The methods of promoting apoptosis of cancer cells involve the co-administration to the cancer cells of a cyclin dependent kinase inhibitor and an agent that induces cell differentiation. The method for treating cancer involves the co-administration of a cyclin dependent kinase inhibitor and an agent that induces cellular differentiation to a patient. Examples of cyclin dependent kinase inhibitors include histone deacetylase inhibitors, protein kinase C activators, retinoids, and Vitamin D3.

Combination Of A) N-{5-[4-(4-Methyl-Piperazino-Methyl)-Benzoylamido]2-Methylphenyl}-4- (3-Pyridyl)-2-Pyrimidine-Amine And B) A Histone Deacetylase Inhibitor For The Treatment Of Leukemia

US Patent:
2006010, May 11, 2006
Filed:
Sep 10, 2003
Appl. No.:
10/527553
Inventors:
Paul Dent - Glen Allen VA, US
Steven Grant - Richmond VA, US
Geoffrey Krystal - Richmond VA, US
Chunrong Yu - Rochester MN, US
International Classification:
A61K 38/12
A61K 31/506
A61K 31/405
A61K 31/19
US Classification:
514009000, 514252180, 514419000, 514557000, 514575000
Abstract:
The invention pertains to a combination of a histone deacetylase inhibitor and N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine or a pharmaceutically acceptable salt thereof for simultaneous, separate or sequential use for the treatment of leukemia and especially N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-resistant leukemia.

Mda-7 And Free Radicals In The Treatment Of Cancer

US Patent:
2006011, May 25, 2006
Filed:
Jun 22, 2005
Appl. No.:
11/158743
Inventors:
Paul Fisher - Scarsdale NY, US
Rahul Gopalkrishnan - New York NY, US
Irina Lebedeva - Bronx NY, US
Steven Grant - Richmond VA, US
Adly Yacoub - Richmond VA, US
Paul Dent - Glen Allen VA, US
International Classification:
A61K 48/00
US Classification:
424093210, 514044000
Abstract:
The present invention relates to methods of treating a cancer in a subject comprising generating within one or more cancer cells of a subject an effective amount of MDA-7 and an effective amount of one or more free radicals. The present invention further relates to methods of inhibiting proliferation or promoting death in a cancer cell of a subject comprising generating within one or more cancer cells of a subject an effective amount of MDA-7 and an effective amount of one or more free radicals. Generation of an effective amount of MDA-7 can occur by administering to the cancer cell an effective amount of an mda-7 nucleic acid, MDA-7 protein, functional equivalents of either of these molecules, by upregulation of the endogenous mda-7 gene, or by stabilization of the mda-7 mRNA. Generation of one or more free radicals in a cancer cell can occur by exposing the cancer cell to an effective amount of ionizing radiation, a free radical, a generator of a free radical, a ROS, a generator of a ROS, or a disruptor of mitochondrial membrane potential.

Combination Therapy

US Patent:
2009010, Apr 23, 2009
Filed:
Jan 23, 2008
Appl. No.:
12/009867
Inventors:
Mitchell Keegan - Marlborough MA, US
Steven Grant - Richmond VA, US
International Classification:
A61K 31/56
A61K 31/395
C12N 5/02
A61P 35/04
A61K 31/4965
US Classification:
514171, 514431, 51425506, 435375
Abstract:
The invention provides a combination therapy for treating cancer and other neoplasms including romidepsin and a proteasome inhibitor. When administered together, romidepsin and a proteasome inhibitor (e.g., bortezomib) interact synergistically to selectively kill malignant cells at low (nanomolar) concentrations. The effect is particularly pronounced in malignant hematological cells (e.g., leukemia, lymphoma, multiple myeloma). The combination has also been found useful in treating bortezomib-resistant cancers and steroid-resistant cancers. The invention provides methods of killing malignant cells in vitro and in vivo. Pharmaceutical compositions, preparations, and kits including romidepsin and a proteasome inhibitor are also provided.

Combination Of A) N--4-(3-Pyridyl)-2-Pyrimidine-Amine And B) A Histone Deacetylase Inhibitor For The Treatment Of Leukemia

US Patent:
2009026, Oct 22, 2009
Filed:
Jun 19, 2009
Appl. No.:
12/456669
Inventors:
Paul Dent - GlenAllen VA, US
Steven Grant - Richmond VA, US
Geoffrey Krystal - Richmond VA, US
Chunrong Yu - Rochester MN, US
International Classification:
A61K 31/497
US Classification:
51425218
Abstract:
The invention pertains to a combination of a histone deacetylase inhibitor and N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine or a pharmaceutically acceptable salt thereof for simultaneous, separate or sequential use for the treatment of leukemia and especially N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-resistant leukemia.

Specific Inhibition Of The P42/44 Mitogen Activated Protein (Map) Kinase Cascade Sensitizes Tumor Cells

US Patent:
6147107, Nov 14, 2000
Filed:
Dec 20, 1998
Appl. No.:
9/203342
Inventors:
Paul Dent - Glen Allen VA
Steven Grant - Richmond VA
W. David Jarvis - Richmond VA
Assignee:
Virginia Commonwealth University - Richmond VA
International Classification:
A01N 4302
A61K 31335
US Classification:
514449
Abstract:
Mammaliam cancer cells are effectively killed when treated with a lethal agent (e. g. radiation or chemotherapeutic agents) in combination with an inhibitor specific for the p42/44 MAP kinase cascade "proper".

Isbn (Books And Publications)

The Russian Empire And Soviet Union: A Guide To Manuscripts And Archival Materials In The United States

Author:
Steven A. Grant
ISBN #:
0816113009

Scholars' Guide To Washington, D.c. For Russian/Soviet Studies

Author:
Steven A. Grant
ISBN #:
0874744849

Scholars' Guide To Washington, D.c. For Russian/Soviet Studies

Author:
Steven A. Grant
ISBN #:
0874744857

Scholars' Guide To Washington, D. C. For Russian, Central Eurasian, And Baltic Studies: The Baltic States, Byelorussia, Central Asia, Moldavia, Russia, Transcaucasia, The Ukraine

Author:
Steven A. Grant
ISBN #:
0874744903

The Teleconnect Guide To Automatic Call Distributors

Author:
Steven C Grant
ISBN #:
0936648082

Hamlet

Author:
Steven Grant
ISBN #:
0425120260

The Count Of Monte Cristo

Author:
Steven Grant
ISBN #:
0425120287

The Island Of Dr. Moreau

Author:
Steven Grant
ISBN #:
0425120295

Possible Relatives

David J Grant  Cyril D Grant  Davina L Grant  Dawn A Grant  Deandre M Grant  Deanna L Grant  Daisy Grant  Steven J Last  Steven M Johnson  Steven S Stamps 

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