Sudhir Kumar Sinha, Age 804908 Guidry St, Metairie, LA 70006

Sudhir Sinha Phones & Addresses

4908 Guidry St, Metairie, LA 70006 (504) 875-4336

5027 Yale St, Metairie, LA 70006

Carrollton, TX

New Orleans, LA

Cupertino, CA

Hammond, LA

Columbus, OH

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Mentions for Sudhir Kumar Sinha

Career records & work history

Medicine Doctors

Sudhir K. Sinha

Specialties:
Internal Medicine
Work:
Sudhir K Sinha MD
24 E Whitney Ave STE 2, Shelby, OH 44875
(419) 347-2525 (phone) (419) 347-8558 (fax)
Ohio Medical Associates
341 Cline Ave Lowr Lvl, Mansfield, OH 44907
(419) 756-8998 (phone) (419) 756-9733 (fax)
Education:
Medical School
Rajendra Med Coll, Ranchi Univ, Ranchi, Bihar, India
Graduated: 1980
Procedures:
Arthrocentesis, Continuous EKG, Electrocardiogram (EKG or ECG)
Conditions:
Bronchial Asthma, Cardiac Arrhythmia, Contact Dermatitis, Diabetes Mellitus (DM), Disorders of Lipoid Metabolism, Hypertension (HTN), Hypothyroidism, Ischemic Heart Disease, Non-Toxic Goiter, Skin and Subcutaneous Infections, Abdominal Hernia, Abnormal Vaginal Bleeding, Acne, Acute Bronchitis, Acute Pancreatitis, Acute Pharyngitis, Acute Renal Failure, Acute Sinusitis, Acute Upper Respiratory Tract Infections, Alopecia Areata, Alzheimer's Disease, Anal or Rectal Abscess, Anemia, Anxiety Dissociative and Somatoform Disorders, Anxiety Phobic Disorders, Atrial Fibrillation and Atrial Flutter, Attention Deficit Disorder (ADD), Bell's Palsy, Benign Polyps of the Colon, Benign Prostatic Hypertrophy, Burns, Calculus of the Urinary System, Cholelethiasis or Cholecystitis, Chronic Bronchitis, Cirrhosis, Constipation, Dementia, Diverticulitis, Diverticulosis, Emphysema, Erectile Dysfunction (ED), Esophagitis, Fractures, Dislocations, Derangement, and Sprains, Gastritis and Duodenitis, Gastroesophageal Reflux Disease (GERD), Gastrointestinal Hemorrhage, Glaucoma, Gout, Heart Failure, Hemorrhoids, Herpes Simplex, Herpes Zoster, Hyperthyroidism, Inguinal Hernia, Intestinal Obstruction, Irritable Bowel Syndrome (IBS), Ischemic Stroke, Malignant Neoplasm of Female Breast, Menopausal and Postmenopausal Disorders, Migraine Headache, Osteoarthritis, Osteoporosis, Otitis Media, Overweight and Obesity, Peripheral Nerve Disorders, Phlebitis and Thrombophlebitis, Pneumonia, Pulmonary Embolism, Restless Leg Syndrome, Sciatica, Tinea Unguium, Transient Cerebral Ischemia, Urinary Incontinence, Urinary Tract Infection (UT), Venous Embolism and Thrombosis, Ventral Hernia, Viral Meningitis
Languages:
English
Description:
Dr. Sinha graduated from the Rajendra Med Coll, Ranchi Univ, Ranchi, Bihar, India in 1980. He works in Mansfield, OH and 1 other location and specializes in Internal Medicine. Dr. Sinha is affiliated with Ohiohealth Mansfield Hospital and Ohiohealth Medcentral Shelby Hospital.

Sudhir Sinha resumes & CV records

Resumes

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Sudhir Sinha

Publications & IP owners

Us Patents

Assay For Human Dna For Gender Determination

US Patent:
7074567, Jul 11, 2006
Filed:
Sep 30, 2003
Appl. No.:
10/673854
Inventors:
Sudhir K. Sinha - Metairie LA, US
Dale J. Hedges - Baton Rouge LA, US
Mark A. Batzer - Mandeville LA, US
Assignee:
Reliagene Technologies Inc. - New Orleans LA
Board of Supervisors Of Louisiana State University and Agricultural and Mechanical college - Baton Rouge LA
International Classification:
C12Q 1/68
C12P 19/34
C07H 21/02
US Classification:
435 6, 435 912, 536 231
Abstract:
A method for determining gender from a human DNA sample. The loci of Alu element insertion is selected, amplified and evaluated in terms of size of the fragment. The gender assay utilizes AluSTXa for the X chromosome, AluSTYa for the Y chromosome, or both AluSTXa and AluSTYa, to reduce the possibility of error to a negligible quantity. The inserted chromosome yields a large fragment when the homologous region is amplified. The males are distinguished as having two DNA amplicons present, while females have only a single amplicon. The kit adapted for carrying out the method includes a pair of primers to amplify the locus and optionally polymerase chain reaction regents.

Multiplex Pcr For Simultaneous Quantitation Of Human Nuclear, Mitochondrial, And Male Y-Chromosome Dna

US Patent:
7405044, Jul 29, 2008
Filed:
Oct 7, 2005
Appl. No.:
11/245444
Inventors:
Jerilyn A. Walker - Breaux Bridge LA, US
Dale J. Hedges - Plaquemine LA, US
Jaiprakash G. Shewale - New Orleans LA, US
Sudhir K. Sinha - New Orleans LA, US
Mark A. Batzer - Mandeville LA, US
Assignee:
Reliagene Technologies Inc. - New Orleans LA
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College - Baton Rouge LA
International Classification:
C12Q 1/68
C12P 19/34
C07H 21/04
US Classification:
435 6, 435 912, 536 231, 536 2431, 536 2433
Abstract:
A comprehensive set of human specific, target specific, multiplex PCR assays for DNA quantitation is provided. Our duplex qPCR for nDNA/mtDNA had a linear quantitation range of 100 ng to 1 pg, and our triplex qPCR assay for nDNA/mtDNA/male Y DNA had a linear range of 100 ng to 0. 1 ng. Human-specificity was demonstrated by the accurate detection of 0. 05% and 5% human DNA, respectively, from a complex source of starting templates. Target-specificity was confirmed by the lack of cross-amplification among targets. A high throughput alternative for human gender determination was also developed by multiplexing the male Y primer/probe set with an X chromosome based system. Background cross-amplification with DNA templates derived from fourteen other species was negligible aside from the male Y assay which produced spurious amplifications from other non-human primate templates. Mainstream application of these assays will undoubtedly benefit forensic genomics.

Assay For Human Dna For Gender Determination

US Patent:
7432362, Oct 7, 2008
Filed:
May 10, 2006
Appl. No.:
11/431030
Inventors:
Sudhir K. Sinha - New Orleans LA, US
Dale J. Hedges - Plaquemine LA, US
Mark A. Batzer - Mandeville LA, US
Assignee:
Reliagene Technologies Inc. - New Orleans LA
Board of Supervisors of Louisiana State University and Agricultural and Medical College - Baton Rouge LA
International Classification:
C07H 21/02
US Classification:
536 231, 435975
Abstract:
A method for determining gender from a human DNA sample. The loci of Alu element insertion is selected, amplified and evaluated in terms of size of the fragment. The gender assay utilizes AluSTXa for the X chromosome, AluSTYa for the Y chromosome, or both AluSTXa and AluSTYa, to reduce the possibility of error to a negligible quantity. The inserted chromosome yields a large fragment when the homologous region is amplified. The males are distinguished as having two DNA amplicons present, while females have only a single amplicon. The kit adapted for carrying out the method includes a pair of primers to amplify the locus and optionally polymerase chain reaction regents.

Assay For Quantitation Of Human Dna Using Elements

US Patent:
7537889, May 26, 2009
Filed:
Sep 30, 2003
Appl. No.:
10/673575
Inventors:
Sudhir K. Sinha - Metairie LA, US
Jerilyn A. Walker - Breaux Bridge LA, US
Mark A. Batzer - Mandeville LA, US
Assignee:
Life Genetics Lab, LLC. - New Orleans LA
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College - Baton Rouge LA
International Classification:
C12Q 1/68
US Classification:
435 6
Abstract:
An assay for determining presence of human DNA in a sample in which non-human DNA may also be present and for quantitating such human DNA. One embodiment uses intra-Alu based PCR and another uses inter-Alu based PCR. The assays are performed without unique, expensive equipment. The assays are based on detection of multiple-copy Alu elements recently integrated into the human genome that are largely absent from non-human primates and other mammals.

Assay For Species Sources

US Patent:
7582452, Sep 1, 2009
Filed:
Dec 17, 2003
Appl. No.:
10/736912
Inventors:
Sudhir K. Sinha - Metairie LA, US
Jaiprakash G. Shewale - Metairie LA, US
Jerilyn A. Walker - Breaux Bridge LA, US
Mark A. Batzer - Mandeville LA, US
Assignee:
Life Genetics Lab, LLC - New Orleans LA
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College - Baton Rouge LA
International Classification:
C12Q 1/68
C12P 19/34
US Classification:
435 912, 435 6, 435 911
Abstract:
A family of PCR assays is disclosed for determining, both qualitatively and quantitatively, presence of material from a predetermined species source and for quantifying the amount of such material. The assays are based respectively on SINEs uniquely characteristic of pig species, cow species, chicken species, and ruminant sub-order, and having a high copy number. The assays disclosed permit rapid, inexpensive evaluation of meat samples to facilitate elimination from their diet of pork or beef by persons desiring to avoid such food sources; as well as the assay of cattle feed to determine presence therein of ruminant-source proteins, which are a potential source of bovine spongiform encephalopathy (BSE), commonly referred to as “mad cow disease. ” The assays amplify the predetermined unique SINEs and the resulting amplified mixture is then evaluated qualitatively by electrophoresis on gel containing ethidium bromide or quantitatively by SYBR Green-based detection or TaqMan chemistry. The invention also extends to kits, primers, and other products used in connection with the assays.

Method For Genetic Detection Using Interspersed Genetic Elements

US Patent:
7794983, Sep 14, 2010
Filed:
Jul 11, 2007
Appl. No.:
11/826020
Inventors:
Sudhir K. Sinha - New Orleans LA, US
Anthony B. Carter - New Orleans LA, US
Assignee:
Life Genetics Lab, LLC. - Metairie LA
International Classification:
C12P 19/34
C07H 21/04
US Classification:
435 912, 536 2433
Abstract:
The way to design a “filled” site (which contains an interspersed element) primer set to target a particular locus is to design one of the two primers such that it encompasses that unique information (e. g. , interspersed element+flanking genomic sequence+direct repeat). The way to design an “empty” site primer is to design one of the two primers such that the entire direct repeat sequence in addition to flanking genomic sequence is included on both sides. To improve efficiency, the “empty” site primer designed around the direct repeat should not be too long. This primer design of the present invention allows for the ability to test any type of interspersed genetic element containing characteristic direct repeat sequences (direct repeats). This gives the option of many new polymorphic marker sites because Alu elements are not the only interspersed genetic elements having direct repeats flanking their core sequence.

Assay For Species Sources

US Patent:
7927841, Apr 19, 2011
Filed:
Jul 10, 2009
Appl. No.:
12/458422
Inventors:
Sudhir K. Sinha - Metairie LA, US
Jaiprakash G. Shewale - Metairie LA, US
Jerilyn A. Walker - Breaux Bridge LA, US
Mark A. Batzer - Mandeville LA, US
Assignee:
Life Genetics Lab, LLC. - Metairie LA
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College - Baton Rouge LA
International Classification:
C12Q 1/68
C12P 19/34
US Classification:
435 912, 435 6, 435 911
Abstract:
A family of PCR assays is disclosed for determining, both qualitatively and quantitatively, presence of material from a predetermined species source and for quantifying the amount of such material. The assays are based respectively on SINEs uniquely characteristic of pig species, cow species, chicken species, and ruminant sub-order, and having a high copy number. The assays disclosed permit rapid, inexpensive evaluation of meat samples to facilitate elimination from their diet of pork or beef by persons desiring to avoid such food sources; as well as the assay of cattle feed to determine presence therein of ruminant-source proteins, which are a potential source of bovine spongiform encephalopathy (BSE), commonly referred to as “mad cow disease. ” The assays amplify the predetermined unique SINEs and the resulting amplified mixture is then evaluated qualitatively by electrophoresis on gel containing ethidium bromide or quantitatively by SYBR Green-based detection or TaqMan chemistry. The invention also extends to kits, primers, and other products used in connection with the assays.

Novel Method For Separation Of Human Sperm From Biological Samples For Application In Human Identification

US Patent:
2006014, Jun 29, 2006
Filed:
Dec 2, 2005
Appl. No.:
11/292286
Inventors:
Sudhir Sinha - New Orleans LA, US
Jaiprakash Shewale - New Orleans LA, US
International Classification:
C12Q 1/68
US Classification:
435006000, 435325000
Abstract:
The development of an isolation methodology for separation of human sperm cells from biological samples containing human epithelial cells is provided. Using sperm binding proteins, glycopeptides, lectins, derivatives of N-acetylglucosamine, triazine dyes or inhibitors of glycosyltransferase linked to an insoluble support, our invention enables binding of human sperm cells from biological samples. Bound sperms can be dissociated and used for in vitro analyses or subsequently lysed on the insoluble support for isolation of male specific DNA. Other cell types such as epithelial cells, white blood cells and cell debris present in the biological samples are not bound to the derivatized insoluble support. The sperm cells, thus isolated, can be processed for isolation of nuclear DNA for human identification and forensic DNA analysis.

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