Inventors:
Thomas Newmark - Brattleboro VT, US
Robert Newman - Houston TX, US
Peiying Yang - Sugar Land TX, US
Paul Schulick - Brattleboro VT, US
Assignee:
New Chapter Inc. - Brattleboro VT
Board of Regents of the University of Texas System - Austin TX
International Classification:
A61K 36/00
A61K 36/82
A61K 36/53
A61K 36/906
US Classification:
424725, 424729, 424745, 424756, 424777
Abstract:
The inventive subject matter relates to methods for treating oral cancers, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, , rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1α, interleukin-1β, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.