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Us Patents
Engineered Microorganisms Having Resistance To Ionic Liquids
US Patent:
2016009, Mar 31, 2016
Filed:
May 20, 2015
Appl. No.:
14/717962
Inventors:
- Livermore CA, US
Douglas A. Higgins - Point Pleasant NJ, US
Thomas L. Ruegg - Berkeley CA, US
Douglas A. Higgins - Point Pleasant NJ, US
Thomas L. Ruegg - Berkeley CA, US
Assignee:
Lawrence Livermore National Security, LLC - Livermore CA
International Classification:
C07K 14/39
C07K 14/255
C12P 7/02
C07K 14/255
C12P 7/02
Abstract:
The present invention provides for a method of genetically modifying microorganisms to enhance resistance to ionic liquids using a yeast Major Facilitator Superfamily (MFS), or a MFS SmvA Pump or SmvR Regulator, a Small Multidrug Resistance Family (SMR), or YDR090C, polypeptide, host cells genetically modified in accordance with the methods, and methods of using the host cells in a reaction comprising biomass that has been pretreated with ionic liquids.
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