Tie Quan Wei, Age 686548 Helmsley Cir, Windermere, FL 34786
Tie Wei Phones & Addresses
Windermere, FL
Bear, DE
Wilmington, DE
New Castle, DE
Newark, DE
Chicago, IL
97 Ascension Dr, Wilmington, DE 19808 (302) 283-1075
Work
Position:
Sales Occupations
Education
Degree:
Associate degree or higher
Mentions for Tie Quan Wei
Publications & IP owners
Us Patents
Outlier Rejection Method In An Automatic Clinical Analyzer
US Patent:
7039561, May 2, 2006
Filed:
Jun 10, 2004
Appl. No.:
10/865081
Inventors:
Tie Quan Wei - Bear DE, US
Assignee:
Dade Behring Inc. - Deerfield IL
International Classification:
G06F 15/00
H03F 1/26
H04B 15/00
H03F 1/26
H04B 15/00
US Classification:
702191, 702189, 702190
Abstract:
Automatically rejecting outlier measurements in an analytical method employing multiple photometric values by determining the photometric value that is involved in the pair of photometric values having the greatest variance between individual mean rates and the mean rate of all of the multiple photometric values.
Reduction Of Non-Specific Binding In Assays
US Patent:
7172906, Feb 6, 2007
Filed:
Nov 16, 2004
Appl. No.:
10/989677
Inventors:
Zhu Teng - Boothwyn PA, US
Jeffrey L. Moore - Newark DE, US
Alan R. Craig - Wilmington DE, US
Gary Hickey - Hockessin DE, US
Carsten Schelp - Hockessin DE, US
Tie Quan Wei - Bear DE, US
Jeffrey L. Moore - Newark DE, US
Alan R. Craig - Wilmington DE, US
Gary Hickey - Hockessin DE, US
Carsten Schelp - Hockessin DE, US
Tie Quan Wei - Bear DE, US
Assignee:
Dade Behring Inc. - Deerfield IL
International Classification:
G01N 33/548
G01N 33/544
G01N 33/547
G01N 33/53
G01N 1/17
G01N 33/544
G01N 33/547
G01N 33/53
G01N 1/17
US Classification:
436529, 436528, 436532, 435 71, 435 792, 530402
Abstract:
Methods and compositions are disclosed for reducing non-specific binding in a binding assay for the determination of an analyte in a sample where one of the reagents for conducting the binding assay comprises a solid support comprising a polysaccharide. The method comprises including in an assay medium for conducting the binding assay a soluble compound comprising a protein linked to a polysaccharide. Also disclosed are methods and compositions for determining the presence and/or amount of an analyte in a sample suspected of containing the analyte. The methods include as reagents a solid support comprising a polysaccharide and a soluble compound comprising a protein linked to a polysaccharide.
Method And Composition Useful For Determining Fk 506
US Patent:
7186518, Mar 6, 2007
Filed:
Nov 21, 2003
Appl. No.:
10/719868
Inventors:
Chengrong Wang - Glen Mills PA, US
Tie Q. Wei - Bear DE, US
Zhu Teng - Boothwyn PA, US
Tie Q. Wei - Bear DE, US
Zhu Teng - Boothwyn PA, US
Assignee:
Dade Behring Inc. - Deerfield IL
International Classification:
G01N 33/535
G01N 33/533
G01N 33/534
G01N 33/553
G01N 33/533
G01N 33/534
G01N 33/553
US Classification:
435 792, 435 793, 436526, 436544, 436545, 436546, 436815, 436825
Abstract:
New derivatives of FK 506 are disclosed. These new derivatives and other derivatives that are useful for determining the levels of FK 506 in a sample are also provided as are assay procedures and kits for use in determining the levels of FK 506 or other macrophilin binding substances in blood, particularly un-extracted blood in the presence of specific binding proteins for FK 506.
Reduction Of Non-Specific Binding In Assays
US Patent:
7488608, Feb 10, 2009
Filed:
Jan 3, 2007
Appl. No.:
11/619244
Inventors:
Zhu Teng - Boothwyn PA, US
Jeffrey L. Moore - Newark DE, US
Alan R. Craig - Wilmington DE, US
Gary Hickey - Hockessin DE, US
Carsten Schelp - Hockessin DE, US
Tie Quan Wei - Bear DE, US
Jeffrey L. Moore - Newark DE, US
Alan R. Craig - Wilmington DE, US
Gary Hickey - Hockessin DE, US
Carsten Schelp - Hockessin DE, US
Tie Quan Wei - Bear DE, US
Assignee:
Siemens Healthcare Diagnostics Inc. - Deerfield IL
International Classification:
G01N 33/548
G01N 33/544
G01N 33/547
G01N 33/53
C07K 17/10
G01N 33/544
G01N 33/547
G01N 33/53
C07K 17/10
US Classification:
436529, 436523, 436528, 436532, 436533, 435 71, 435 792, 530402, 530403
Abstract:
Methods and compositions are disclosed for reducing non-specific binding in a binding assay for the determination of an analyte in a sample where one of the reagents for conducting the binding assay comprises a solid support comprising a polysaccharide. The method comprises including in an assay medium for conducting the binding assay a soluble compound comprising a protein linked to a polysaccharide. Also disclosed are methods and compositions for determining the presence and/or amount of an analyte in a sample suspected of containing the analyte. The methods include as reagents a solid support comprising a polysaccharide and a soluble compound comprising a protein linked to a polysaccharide.
Tacrolimus Standard And Methods Of Using Same
US Patent:
7642338, Jan 5, 2010
Filed:
Jun 20, 2006
Appl. No.:
11/455956
Inventors:
Tie Q. Wei - Bear DE, US
David R. Hudson - Rising Sun MD, US
David R. Hudson - Rising Sun MD, US
Assignee:
Siemens Healthcare Diagnostics Inc. - Deerfield IL
International Classification:
A61K 38/12
G01N 33/566
A61B 5/00
G01N 33/566
A61B 5/00
US Classification:
530317, 436501, 600300
Abstract:
A composition and kit useful as a tacrolimus standard solution for immunoassays, and methods for making and using same. The composition and kits include a known amount of tacrolimus or a derivative thereof, and a non-specific protein capable of forming a complex with the tacrolimus or derivative thereof. The standard solution may be used to generate calibration curves for an immunoassay or to check the precision of an analytical instrument.
Methods For Detection Of Immunosuppressant Drugs
US Patent:
7790401, Sep 7, 2010
Filed:
Aug 6, 2007
Appl. No.:
11/834173
Inventors:
Tie Q. Wei - Bear DE, US
Gerald Siefring, Jr. - Wilmington DE, US
Christy Schaible - Oxford PA, US
Amy Posey - Cochranville PA, US
Gerald Siefring, Jr. - Wilmington DE, US
Christy Schaible - Oxford PA, US
Amy Posey - Cochranville PA, US
Assignee:
Siemens Healthcare Diagnostics - Deerfield IL
International Classification:
G01N 33/53
US Classification:
435 71, 436518
Abstract:
Methods and reagents are disclosed for enhancing the bioavailability of a hydrophobic drug, and in some embodiments for determining a hydrophobic drug, in a sample suspected of containing a hydrophobic drug. A combination is formed in a medium where the combination comprises the sample, a hemolytic agent where a determination of the hydrophobic drug is conducted, and a bioavailability agent for the hydrophobic drug. The bioavailability agent comprises an ionic detergent comprising a chain of at least 10 carbon atoms or a non-ionic detergent comprising a chain of at least 15 repeating ethylene oxide units or propylene oxide units or a combination of ethylene oxide units and propylene oxide units. The concentration of the bioavailability agent in the medium is sufficient to enhance the bioavailability of the hydrophobic drug. The medium is incubated under conditions for enhancing the bioavailability of the hydrophobic drug, and in a determination of the hydrophobic drug under conditions for hemolyzing cells in the sample.
Stabilization Of Solid Support Assay Reagents
US Patent:
7842475, Nov 30, 2010
Filed:
Jan 8, 2008
Appl. No.:
11/970658
Inventors:
Yi Feng Zheng - Wilmington DE, US
Tie Q. Wei - Bear DE, US
Tie Q. Wei - Bear DE, US
Assignee:
Siemens Healthcare Diagnostics Inc. - Deerfield IL
International Classification:
G01N 33/53
US Classification:
435 75, 435 71, 4352831, 4352872, 4352879, 436518, 436524, 436527
Abstract:
Reagents are disclosed for use in assays for analytes. The reagents are dry assay reagents that may be readily reconstituted for use in the assays. The dry assay reagents comprise a solid support and one or more molecules of a receptor immobilized on the solid support. The receptor comprises one or more binding sites for a ligand. A portion of a total number of the binding sites is bound to a conjugate comprising the ligand linked to a specific binding pair member and a portion of the total number of the binding sites is free. In use in an assay, a combination is provided in an aqueous medium comprising the sample and reagents for detecting the analyte wherein at least one of the reagents comprises the dry assay reagent mentioned above. The combination is incubated under conditions for binding of the analyte to one or more of the reagents. The presence and/or amount of binding of the analyte to one or more of the reagents is detected where the presence and/or amount of the binding is related to the presence and/or amount of the analyte in the sample.
Methods For Detection Of Hydrophobic Drugs
US Patent:
7910378, Mar 22, 2011
Filed:
Dec 14, 2007
Appl. No.:
11/956603
Inventors:
Tie Q. Wei - Bear DE, US
Alan R. Craig - Wilmington DE, US
Amy Posey - Cochranville PA, US
Alan R. Craig - Wilmington DE, US
Amy Posey - Cochranville PA, US
Assignee:
Siemens Healthcare Diagnostics Inc. - Deerfield IL
International Classification:
G01N 1/18
US Classification:
436177, 436522, 436 17, 436174, 436175, 436176, 436179, 424 92, 435962, 530412
Abstract:
Methods and reagents are disclosed for pretreating a sample suspected of containing a hydrophobic drug for conducting an assay method for detecting the hydrophobic drug. A combination is provided in a medium. The combination comprises (i) the sample, (ii) a releasing agent for releasing the hydrophobic drug and the metabolites from endogenous binding moieties, and (iii) a selective solubility agent that provides for substantially equal solubility of the hydrophobic drug and the metabolites in the medium. The selective solubility agent comprises a water miscible, non-volatile organic solvent and is present in the medium in a concentration sufficient to provide for substantially equal solubility of the hydrophobic drug and the metabolites in the medium. The medium, which may further comprise a hemolytic agent, is incubated under conditions for releasing the hydrophobic drug and the metabolites from endogenous binding moieties. For conducting an assay for the hydrophobic drug, the above pretreatment is performed and to the medium is added reagents for determining the presence and/or amount of the hydrophobic drug in the sample wherein the reagents comprise at least one antibody for the hydrophobic drug.
Possible Relatives
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