Inventors:
Vaibhav Varkhedkar - Sunnyvale CA
Venkata P. Palle - Mountain View CA
Jeff Zablocki - Mountain View CA
Elfatih Elzein - Fremont CA
Brent K. Blackburn - Los Altos CA
Assignee:
CV Therapeutics, Inc. - Palo Alto CA
International Classification:
A61K 31495
Abstract:
Novel compounds of the general formula: and pharmaceutically acceptable acid addition salts thereof, wherein the compounds are useful in therapy to protect skeletal muscles against damage resulting from trauma or to protect skeletal muscles subsequent to muscle or systemic diseases such as intermittent claudication, to treat shock conditions, to preserve donor tissue and organs used in transplants, in the treatment of cardiovascular diseases including atrial and ventricular arrhythmias, Prinzmetals (variant) angina, stable angina, and exercise induced angina, congestive heart disease, and myocardial infarction.