William Joseph Foye, Age 7410 Nutt Rd, Auburn, NH 03032

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10 Nutt Rd, Auburn, NH 03032 (603) 622-6703

28 Nutt Rd, Auburn, NH 03032 (603) 622-6703

Manchester, NH

Belmont, MA

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Us Patents

N-Sugar Compounds, Compositions And Uses Thereof

US Patent:
4367226, Jan 4, 1983
Filed:
Dec 2, 1980
Appl. No.:
6/212198
Inventors:
William O. Foye - Lexington MA
International Classification:
A61K 3170
C07H 1900
C07H 1700
C07H 502
US Classification:
424180
Abstract:
Novel, water-soluble antimicrobial compounds are provided which contain a sugar moiety linked to a nitrogen atom of substituted thiourea or a thiazole. The compounds have the general formula: ##STR1## and the pharmaceutically acceptable salts thereof wherein Su is a sugar moiety, i. e. , mono- or polysaccharide and preferably glucosyl or acylated (i. e. C. sub. 2 to C. sub. 6 alkanoyl e. g. acetyl, propionyl, butyroyl etc. or aroyl e. g. benzoyl or C. sub. 1 to C. sub. 4 alkyl or alkoxy substituted benzoyl) ribosyl; and in Formula I, R. sub. 1 and R. sub. 2 are independently hydrogen, C. sub. 1 to C. sub. 8 alkyl or alkoxy; C. sub. 1 to C. sub. 8. omega. -phenyl-(or substituted phenyl)-substituted C. sub. 1 to C. sub. 8 alkyl; C. sub. 3 to C. sub. 8 alkene, preferably allyl; ##STR2## wherein R. sub. 3 and R. sub.

Isbn (Books And Publications)

Principles Of Medicinal Chemistry

Author:
William O. Foye
ISBN #:
0683033239

Principles Of Medicinal Chemistry

Author:
William O. Foye
ISBN #:
0812104455

Principles Of Medicinal Chemistry

Author:
William O. Foye
ISBN #:
0812107225

Principles Of Medicinal Chemistry

Author:
William O. Foye
ISBN #:
0812110986

Cancer Chemotherapeutic Agents

Author:
William O. Foye
ISBN #:
0841229201

Cancer Chemotherapeutic Agents

Author:
William O. Foye
ISBN #:
0841232164

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