Yun Y XieGlendora, CA

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Glendora, CA

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Compounds And Compositions As Itpkb Inhibitors

US Patent:
2011026, Oct 27, 2011
Filed:
Mar 30, 2009
Appl. No.:
12/935273
Inventors:
Yongqin Wan - Irvine CA,
Shifeng Pan - San Diego CA,
Guobao Zhang - San Diego CA,
Xia Wang - San Diego CA,
Yun Feng Xie - San Diego CA,
Jiqing Jiang - San Diego CA,
Dean Phillips - San Marcos CA,
Yang Yang - San Diego CA,
Assignee:
IRM LLC - Hamilton
International Classification:
C07D 487/04
C07D 405/14
A61P 19/02
A61P 17/06
A61P 37/00
A61K 31/496
C07D 401/14
US Classification:
51425305, 51425304, 51425309, 544362, 544364, 544363
Abstract:
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated B cell activities, particularly diseases or disorders that involve aberrant activation of inositol 1,4,5-trisphosphate 3-kinase B (ITPKb).

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