Feng Lin MiaoHarbor City, CA

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Harbor City, CA

Torrance, CA

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Feng Miao

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Us Patents

Mapping Histone Modifications By Dna Microarray

US Patent:
2007029, Dec 20, 2007
Filed:
Aug 8, 2006
Appl. No.:
11/501662
Inventors:
Rama Natarajan - Hacienda Heights CA, US
Feng Miao - Arcadia CA, US
International Classification:
C12Q 1/68
US Classification:
435006000
Abstract:
Many human diseases are now realized to have epigenetic features. Post-translational modification of histones plays a major role in these epigenetic features. Chromatin immunoprecipitation assay (ChIP) is currently the method of choice for localizing histone modifications in a step-wise fashion. This technique utilizes histone modification-specific antibodies to enrich DNA (ChIP DNA), followed by the use of promoter-specific primers to localize the modification. Methods of using DNA microarrays to screen ChIPed DNA are provided herein.

Txnip-Trx Complex Inhibitors And Methods Of Using The Same

US Patent:
2022031, Oct 6, 2022
Filed:
Apr 6, 2022
Appl. No.:
17/714569
Inventors:
- Duarte CA, US
Feng Miao - Alhambra CA, US
Nagarajan Vaidehi - Arcadia CA, US
Supriyo Bhattacharya - Monrovia CA, US
Adrien Beau Larsen - Duarte CA, US
International Classification:
A61K 31/437
A61P 3/10
A61K 31/496
A61K 31/4439
A61K 31/5377
A61K 31/4035
Abstract:
Disclosed herein, inter alia, are compounds and methods for inhibiting the thioredoxin-thioredoxin-interacting-protein (TXNIP-TRX) complex.

Txnip-Trx Complex Inhibitors And Methods Of Using The Same

US Patent:
2020008, Mar 19, 2020
Filed:
Sep 13, 2019
Appl. No.:
16/570802
Inventors:
- Duarte CA, US
Feng Miao - Alhambra CA, US
Nagarajan Vaidehi - Arcadia CA, US
Supriyo Bhattacharya - Monrovia CA, US
Adrien Beau Larsen - Duarte CA, US
International Classification:
A61K 31/437
A61P 3/10
A61K 31/4035
A61K 31/4439
A61K 31/5377
A61K 31/496
Abstract:
Disclosed herein, inter alia, are compounds and methods for inhibiting the thioredoxin-thioredoxin-interacting-protein (TXNIP-TRX) complex.

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