Heidi E Hamm, Age 742004 Jordan Dr, Nashville, TN 37218

Heidi Hamm Phones & Addresses

1923 28Th Ave N, Nashville, TN 37208 (615) 953-6968

11 Breckenridge, Nashville, TN 37215 (615) 372-0252

Sanford, ME

Valparaiso, IN

Mount Juliet, TN

506 Roscoe St, Chicago, IL 60657 (773) 929-0621

Mentions for Heidi E Hamm

Heidi Hamm resumes & CV records

Resumes

Heidi Hamm Photo 28

Aileen M Lange And Annie Mary Lyle Chair In Cardiovascular Research And Professor, Pharmacology

Location:
Nashville, TN
Industry:
Research
Work:
Vanderbilt University Medical Center
Chair, Pharmacology
Northwestern University Inst for Neuroscience 1996 - 2000
Professor
Northwestern University Medical School Nov 1995 - Oct 2000
Professor of Molecular Pharmacology and Biological Chemistry
University of Illinois at Chicago College of Medicine 1990 - 1996
Professor
University of Illinois at Chicago 1984 - 1996
Professor of Physiology and Biophysics
Education:
Heidi Hamm
Skills:
Biochemistry, Pharmacology, Molecular Biology, Biophysics, Physiology, Cell Biology, Western Blotting, Cell Culture, Molecular Pharmacology, Confocal Microscopy, Neuroscience, Animal Models, Pcr, Cell Signaling, Immunohistochemistry, Immunofluorescence, In Vitro, Cancer, Protein Expression, Translational Research, Fluorescence Microscopy, Assay Development, In Vivo, Signal Transduction
Languages:
French
Italian
Spanish
Heidi Hamm Photo 29

Heidi Hamm

Heidi Hamm Photo 30

Heidi Hamm

Heidi Hamm Photo 31

Heidi Hamm

Publications & IP owners

Us Patents

Method For Identifying Inhibitors Of G Protein Coupled Receptor Signaling

US Patent:
7208279, Apr 24, 2007
Filed:
May 11, 2001
Appl. No.:
09/852910
Inventors:
Annette Gilchrist - Barrington IL, US
Heidi M. Hamm - Nashville TN, US
Assignee:
Caden Biosciences, Inc. - Madison WI
International Classification:
G01N 33/53
C12Q 1/70
US Classification:
435 71, 435 6, 435 4, 435DIG 15, 435DIG 14
Abstract:
This invention relates to methods for identifying peptides and other compounds which block G protein coupled receptor mediated signaling with high affinity and specificity. Assays developed in conjunction with these methods also are disclosed.

Method For Identifying Modulators Of G Protein Coupled Receptor Signaling

US Patent:
7294472, Nov 13, 2007
Filed:
Apr 11, 2003
Appl. No.:
10/411336
Inventors:
Annette Gilchrist - Barrington IL, US
Heidi M. Hamm - Nashville TN, US
Assignee:
Caden Biosciences - Madison WI
International Classification:
C40B 20/00
C07H 21/04
US Classification:
435 71, 530327, 530300, 435 4, 435DIG 2, 435DIG 14, 435DIG 15
Abstract:
This invention relates to methods for identifying peptides and other compounds which block or enhance G protein coupled receptor mediated signaling with high affinity and specificity and/or which stabilize a particular conformer of a G protein coupled receptor. Assays, methods of treatment and other methods developed in conjunction with these methods also are disclosed.

Inhibitors Of G Protein-Mediated Signaling, Methods Of Making Them, And Uses Thereof

US Patent:
2003016, Aug 28, 2003
Filed:
Feb 24, 2003
Appl. No.:
10/373540
Inventors:
Heidi Hamm - Chicago IL, US
Annette Gilchrist - Lombard IL, US
Assignee:
Northwestern University
International Classification:
C12P021/02
C12N005/06
C07K014/705
C07H021/04
US Classification:
435/069100, 435/320100, 435/325000, 530/350000, 536/023500
Abstract:
The invention provides compositions and methods useful for blocking G protein-mediated signaling events. Compositions provided by the invention relate to carboxy terminal G peptides, and minigenes which encode such peptides. The invention provides methods of making the minigenes, and methods of using either of the minigenes and the G carboxy terminal peptides encoded thereby, to block G protein-mediated signaling events. The invention also provides methods of using either of the minigenes and the G carboxy terminal peptides encoded thereby for the identification of unknown interactions between G proteins and G protein coupled receptors, and for the treatment of pathological disorders associated with G protein-mediated signaling events.

Methods For Treating Malaria By Modulation Of G Protein Function

US Patent:
2004022, Nov 4, 2004
Filed:
Dec 18, 2003
Appl. No.:
10/740368
Inventors:
Kasturi Haldar - Chicago IL, US
Travis Harrison - Chicago IL, US
Jon Lomasney - Oak Park IL, US
Heidi Hamm - Nashville TN, US
International Classification:
A61K031/522
A61K031/137
US Classification:
514/263310, 514/651000
Abstract:
The present invention is directed to methods and pharmaceutical compositions for treating a mammal suffering from malaria or the sequelae of malarial infection, or for preventing a malarial infection, or for ameliorating the symptoms associated with a malarial infection using a therapeutically effective amount of an agent that down regulates G protein mediated functions. Also contemplated are methods for screening for novel compounds that down regulate G protein receptors, and the use of these compounds for treating mammals having malaria.

Method For Identifying Modulators Of G Protein Coupled Receptor Signaling

US Patent:
2007007, Apr 5, 2007
Filed:
Oct 2, 2006
Appl. No.:
11/540733
Inventors:
Annette Gilchrist - Barrington IL, US
Heidi Hamm - Nashville TN, US
Assignee:
cue BIOtech, Inc. - Madison WI
International Classification:
C40B 30/06
C40B 40/10
US Classification:
435007100
Abstract:
This invention relates to methods for identifying peptides and other compounds which block or enhance G protein coupled receptor mediated signaling with high affinity and specificity and/or which stabilize a particular conformer of a G protein coupled receptor. Assays, methods of treatment and other methods developed in conjunction with these methods also are disclosed.

Method For Identifying Inhibitors Of G Protein Coupled Receptor Signaling

US Patent:
2007023, Oct 4, 2007
Filed:
Apr 20, 2007
Appl. No.:
11/785870
Inventors:
Annette Gilchrist - Barrington IL, US
Heidi Hamm - Nashville TN, US
Assignee:
Caden Biosciences - Madison WI
International Classification:
G01N 33/53
US Classification:
435007100, 435375000, 530300000
Abstract:
This invention relates to methods for identifying peptides and other compounds which block G protein coupled receptor mediated signaling with high affinity and specificity. Assays developed in conjunction with these methods also are disclosed.

Dendritic Molecular Intracellular Transporters And Methods Of Making And Using Same

US Patent:
2008022, Sep 11, 2008
Filed:
Aug 23, 2007
Appl. No.:
11/844353
Inventors:
Eva M. Harth - Nashville TN, US
James E. Crowe - Nashville TN, US
Kui Huang - Nashville TN, US
Sharon K. Hamilton - Nashville TN, US
Heidi E. Hamm - Nashville TN, US
Bryan Voss - Nashville TN, US
International Classification:
A61K 38/05
C07C 279/02
C08G 69/02
US Classification:
514 20, 564241, 564236, 525420
Abstract:
In accordance with the purpose(s) of the invention, as embodied and broadly described herein, the invention, in one aspect, relates to compounds comprising the structure:and at least one guanidinium residue, wherein m is zero or a positive integer. Also disclosed are methods of preparing the disclosed compounds. Also disclosed are methods of intracellular delivery comprising administering the disclosed compounds and compositions to a subject. Also disclosed are pharmaceutical compositions comprising a therapeutically effective amount of one or more compounds or compositions of the invention and a pharmaceutically acceptable carrier. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

G Protein Coupled Receptor Signaling Modulation

US Patent:
2008028, Nov 13, 2008
Filed:
Nov 6, 2007
Appl. No.:
11/979594
Inventors:
Annette Gilchrist - Barrington IL, US
Heidi M. Hamm - Nashville TN, US
Assignee:
Caden Biosciences - Madison WI
International Classification:
G01N 33/53
C07K 2/00
C07K 7/06
C12N 15/63
C12N 5/06
C40B 30/04
US Classification:
435 71, 530300, 530327, 506 9, 435375, 4353201, 435325
Abstract:
This invention relates to methods for identifying peptides and other compounds which block or enhance G protein coupled receptor mediated signaling with high affinity and specificity and/or which stabilize a particular conformer of a G protein coupled receptor. Assays, methods of treatment and other methods developed in conjunction with these methods also are disclosed.

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