John C Spicuzza, Age 628815 Bentley Ln, Spring Grove, IL 60081

John Spicuzza Phones & Addresses

8815 Bentley Ln, Spring Grove, IL 60081 (815) 675-6197

Johnsburg, IL

Superior, CO

Wauconda, IL

Highland Park, IL

Superior, CO

Wauconda, IL

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Mentions for John C Spicuzza

John Spicuzza resumes & CV records

Resumes

John Spicuzza Photo 22

John Spicuzza

Location:
Chicago, IL
Industry:
Pharmaceuticals
Work:
Baxter Healthcare Corporation Jul 2011 - Oct 2016
Senior Manager
Education:
University of Wisconsin - Stevens Point Jan 1, 1980 - Dec 31, 1985
Bachelors, Bachelor of Science, Chemistry
Skills:
Fda, Glp, Pharmaceutical Industry, Biotechnology, Hplc, Gmp, Validation, Analytical Chemistry, Lifesciences, Chemistry, Capa, R&D, V&V, Lc Ms, Chromatography, Life Sciences, Good Laboratory Practice, High Performance Liquid Chromatography
John Spicuzza Photo 23

John Spicuzza

John Spicuzza Photo 24

John Spicuzza

Publications & IP owners

Us Patents

Stable Hemoglobin Based Composition And Method To Store Same

US Patent:
5352773, Oct 4, 1994
Filed:
Oct 16, 1992
Appl. No.:
7/962623
Inventors:
Richard L. Kandler - McHenry IL
John C. Spicuzza - Highland Park IL
Assignee:
Baxter International Inc. - Deerfield IL
International Classification:
C07K 1300
A61K 3514
A61K 3700
C07C10352
US Classification:
530385
Abstract:
The present invention relates to a stable hemoglobin based composition having sufficiently low levels of methemoglobin to effectively function as an oxygen carrying solution upon administration to a patient made by the process comprising: a) adding an oxygenated or deoxygenated form of said blood substitute to an oxygen impermeable package, and b) storing said container at from between 5. degree. C. to 45. degree. C. for sufficient time to permit the autoreduction of methemoglobin. The stable hemoglobin based composition includes hemoglobin, modified hemoglobin and/or encapsulated hemoglobin. To effectively function as an oxygen carrying solution upon administration to a patient, the stable hemoglobin based solution cannot have greater than about 50% of said hemoglobin based solution in the methemoglobin form but, preferably no more than about 15%. The invention further relates to a method to store a stable oxygen carrying solution according to the above discussed process.

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