Inventors:
Kevin J. Edgar - Blacksburg VA, US
Bin Li - Blacksburg VA, US
Lynne Taylor - West Lafayette IN, US
Grace Ilevbare - West Lafatette IN, US
Stephanie M. Williams - Cleveland Heights OH, US
International Classification:
A61K 31/12
Abstract:
The present invention relates to delivery systems to enhance the bioavailability of flavonoids to improve human health. Flavonoids of interest include but are not limited to curcumin, resveratrol, ellagic acid, naringenin, and quercetin. Flavonoids are important in part because they are known to have beneficial effects on human health, including cardioprotective, antioxidant, and anticancer effects. Utility has been limited by low bioavailability, both in the sense of requiring high doses and in that it has been difficult to carry out proper dose-response studies in the absence of methods to control the actual dose administered. In addition to pharmaceutical applications, there are potential nutraceutical uses, for example in supplements that might be sold in health food stores and pharmacies.