Rama P Ramanujam Deceased6866 Mcdougal Ct, Dublin, OH 43017

Rama Ramanujam Phones & Addresses

6866 Mcdougal Ct, Dublin, OH 43017

Alexandria, VA

Des Moines, IA

1310 Fairlane Ave, Brookfield, WI 53005

Oklahoma City, OK

Milwaukee, WI

Chicago, IL

Lewis Center, OH

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Us Patents

Compositions Comprising Inhibitors Of Rna Binding Proteins And Methods Of Producing And Using Same

US Patent:
7902166, Mar 8, 2011
Filed:
Apr 20, 2009
Appl. No.:
12/386550
Inventors:
Courtney Houchen - Edmond OK, US
Shrikant Anant - Edmond OK, US
Sripathi M. Sureban - Oklahoma City OK, US
Satish Ramalingam - Oklahoma City OK, US
Dhamalingam Surbramaniam - Oklahoma City OK, US
Rama P. Ramanujam - Dublin OH, US
Assignee:
The Board of Regents of the University of Oklahoma - Norman OK
International Classification:
A01N 43/04
A61K 31/70
C07H 21/02
C07H 21/04
US Classification:
514 44, 536 231, 536 243, 536 2433, 536 245
Abstract:
Compositions for inhibiting RNA binding proteins, as well as methods of producing and using the same, are disclosed herein.

Luminescence Assay Utilizing A Genetically Modified Cell Line

US Patent:
2010000, Jan 14, 2010
Filed:
Jul 24, 2007
Appl. No.:
12/374824
Inventors:
Rama P. Ramanujam - Columbus OH, US
Shrikant Anant - Oklahoma City OK, US
International Classification:
C12Q 1/66
C12Q 1/02
US Classification:
435 8, 435 29
Abstract:
An assay method to identify agents that will reduce the inflammation associated with many diseases, providing a method to determine compliance of patients to clinical protocols. The fundamental tool of the inventive method is luminescence. Genetically modified cells are used to express a complex revealing the potential of certain compounds to prevent or reduce adverse effects. More specifically the invention is a method for the determination of inhibition of a chemical compound comprising: culturing genetically modified cells which express an indicator-luminescent complex; placing said complex in the presence of an agent that essentially totally degrades said complex; measuring the luminescence of the resulting reaction; collecting a sample from a mammal consuming a complementary and alternative medicine (CAM); placing said sample in the presence of said complex; and comparing the level of luminescence from step (c) with the luminescence from step (e) to determine the inhibition of said chemical compound.

Compositions Useful For Cancer Detection And Treatment, A Cancer Stem Cell Model, And Methods Of Production And Use Thereof

US Patent:
2011028, Nov 17, 2011
Filed:
Feb 15, 2011
Appl. No.:
13/027845
Inventors:
Shrikant Anant - St. Louis MO, US
Courtney Houchen - Edmond OK, US
Satish Ramalingam - Kansas City KS, US
Rama Ramanujam - Dublin OH, US
Dharmalingam Subramanlam - Overland Park KS, US
International Classification:
A01K 67/00
G01N 33/566
C12N 15/85
US Classification:
800 10, 435455, 435 792, 436501
Abstract:
DCAMKL-1 has been identified as a biomarker for stem cells, as well as cancer stem cells. Methods of detecting the presence of at least one stem cell, methods of isolating stem cells, and methods of inhibiting growth of cancer cells utilizing DCAMKL-1 are disclosed herein.

Biological Reagent Spheres

US Patent:
5593824, Jan 14, 1997
Filed:
Apr 12, 1995
Appl. No.:
8/420933
Inventors:
Suzanne B. Treml - Whitefish Bay WI
Cristine J. Dall - Shorewood WI
Connie A. Draveling - New Berlin WI
James F. Jolly - Glendale WI
Rama P. Ramanujam - Brookfield WI
Assignee:
Pharmacia Biotech, Inc. - Milwaukee WI
International Classification:
C12Q 100
C12Q 134
C12Q 137
C12P 2106
US Classification:
435 4
Abstract:
A reagent sphere is disclosed comprising at least one biological reagent and a glass-forming filler material in a concentration sufficient to facilitate formation of a glassy, porous composition, wherein the reagent semi-sphere is water soluble and has a T. sub. g sufficient for room temperature stability. At least two carbohydrates are combined to create the reagent sphere. The first carbohydrate is a synthetic high molecular weight polymer. The second carbohydrate is different than the first carbohydrate. A method is provided for making the reagent sphere.

Method And Preparation For Sequential Delivery Of Wax-Embedded, Inactivated Biological And Chemical Reagents

US Patent:
5599660, Feb 4, 1997
Filed:
Dec 2, 1994
Appl. No.:
8/349115
Inventors:
Rama P. Ramanujam - Brookfield WI
Brent A. Burdick - Brookfield WI
Ulf D. Landegren - Upsala, SE
Pierre Sevigny - Upsala, SE
Assignee:
Pharmacia Biotech Inc. - Milwaukee WI
International Classification:
C12Q 168
C12P 1934
C10G 7336
US Classification:
435 4
Abstract:
A method and preparation for the storage and delivery of purified reagents is disclosed. In one aspect, the preparation comprises an amount of a first wax carrier, the first wax carrier having a first melting point, and an amount of a first reagent, wherein first reagent is a substantially purified preparation of at least one biological or chemical reagent. The first wax carrier and the first reagent are combined to form a solid first reagent portion. The solid mixture is combined with a second reagent portion comprised of at least one biological or chemical reagent in an inactive form.

Biological Reagent Spheres

US Patent:
5763157, Jun 9, 1998
Filed:
Jan 6, 1997
Appl. No.:
8/779874
Inventors:
Suzanne B. Treml - Whitefish Bay WI
Cristine J. Dall - Shorewood WI
Connie A. Draveling - New Berlin WI
James F. Jolly - Glendale WI
Rama P. Ramanujam - Brookfield WI
Assignee:
Pharmacia Biotech Inc. - Milwaukee WI
International Classification:
C12Q 100
C12Q 134
C12Q 137
C07H 100
US Classification:
435 4
Abstract:
A reagent sphere is disclosed comprising at least one biological reagent and a glass-forming filler material in a concentration sufficient to facilitate formation of a glassy, porous composition, wherein the reagent semi-sphere is water soluble and has a T. sub. g sufficient for room temperature stability. At least two carbohydrates are combined to create the reagent sphere. The first carbohydrate is a synthetic high molecular weight polymer. The second carbohydrate is different than the first carbohydrate. A method is provided for making the reagent sphere.

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