Shankar S Swaminathan, Age 6825 Potomac Rd, Monmouth Junction, NJ 08852

Shankar Swaminathan Phones & Addresses

25 Potomac Rd, Monmouth Jct, NJ 08852 (732) 274-9405

Monmouth Junction, NJ

8 Albury Way, North Brunswick, NJ 08902 (732) 297-7513

Monmouth, NJ

Houston, TX

Mentions for Shankar S Swaminathan

Shankar Swaminathan resumes & CV records

Resumes

Shankar Swaminathan Photo 31

Executive Director

Location:
Bridgewater, NJ
Industry:
Pharmaceuticals
Work:
Bausch Health Companies Inc.
Executive Director
Bausch + Lomb Sep 2011 - Mar 2014
Senior Manager Regulatory Affairs Cmc
Bristol-Myers Squibb Jan 2006 - Aug 2011
Manager Regulatory Affairs Cmc
Bristol-Myers Squibb Jan 1998 - Dec 2005
Senior Research Investigator
Education:
Ms University of Baroda
Doctorates, Doctor of Philosophy, Organic Chemistry
Department of Technology, Savitribai Phule Pune University
Master of Science, Masters, Organic Chemistry
Purdue University
Skills:
Fda, Cmc, Capa, Drug Development, Regulatory Affairs, Gmp, Biologics, Pharmaceutical Industry, Oncology, Technology Transfer, Change Control, Regulatory Submissions, Nda, Clinical Trials, Chemistry, Cro, Biotechnology, Validation, Ind, Process Optimization
Shankar Swaminathan Photo 32

Group Manager Reg Affairs At Bms

Position:
Sr Manager Reg Affairs at Bausch + Lomb
Location:
Greater New York City Area
Industry:
Pharmaceuticals
Work:
Bausch + Lomb - Madison NJ since Sep 2011
Sr Manager Reg Affairs
Bristol-Myers Squibb, Princeton, New Jersey - New Brunswick NJ Jan 2006 - Aug 2011
Manger Regulatory Affairs CMC
Education:
University of Pune

Publications & IP owners

Us Patents

Enzymatic Oxidative Deamination Process

US Patent:
6515170, Feb 4, 2003
Filed:
Apr 26, 2001
Appl. No.:
09/843226
Inventors:
Ramesh N. Patel - Bridgewater NJ
Amit Banerjee - St. Louis MO
Venkata B. Nanduri - East Brunswick NJ
Steven L. Goldberg - Basking Ridge NJ
Robert M. Johnston - Whitehouse Station NJ
Thomas P. Tully - Middlesex NJ
Laszlo J. Szarka - East Brunswick NJ
Shankar Swaminathan - North Brunswick NJ
John J. Venit - North Brunswick NJ
Jerome L. Moniot - Chester NJ
William J. Winter - New Brunswick NJ
Neal G. Anderson - Stockton NJ
David A. Lust - Roosevelt NJ
Gerard Crispino - Princeton NJ
Sushil K. Srivastava - Dayton NJ
Assignee:
Bristol-Myers Squibb Co. - Princeton NJ
International Classification:
C07C 3200
US Classification:
562432, 562433, 562426, 562485, 562400
Abstract:
The present invention concerns an enzymatic oxidative deamination process of a dipeptide monomer to prepare an intermediate useful to prepare compounds having endopeptidase and angiotensin converting enzyme inhibition activity.

Process For The Preparation Of Epothilone Analogs

US Patent:
6518421, Feb 11, 2003
Filed:
Feb 1, 2001
Appl. No.:
09/775361
Inventors:
Wen Sen Li - Holmdel NJ
John E. Thornton - Newtown PA
Zhenrong Guo - East Brunswick NJ
Shankar Swaminathan - Monmouth Junction NJ
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D49100
US Classification:
540462, 548181
Abstract:
The present invention relates to a process for the preparation of epothilone analogs by initially forming novel ring-opened epothilones and carrying out a macrolactamization reaction thereon. The subject process is amenable to being carried out in a single reaction vessel without isolation of the intermediate compound and provides at least about a three-fold increase in yield over prior processes for preparing the desired epothilone analogs.

Process For Preparing Pyrrolotriazine

US Patent:
7102001, Sep 5, 2006
Filed:
Dec 9, 2004
Appl. No.:
11/008719
Inventors:
Shankar Swaminathan - Monmouth Junction NJ, US
Ashvinikumar V. Gavai - Princeton Junction NJ, US
Junying Fan - Monmouth Junction NJ, US
Bharat P. Patel - Pennington NJ, US
Derek J. Norris - Pennington NJ, US
Richard Michael Corbett - Robbinsville NJ, US
Bin Zheng - Kendall Park NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D 487/14
C07D 413/14
C07D 403/12
A61K 31/53
A61P 35/00
US Classification:
544183, 544132, 5483621
Abstract:
The present invention provides a process for preparing compounds of formula (I)The compounds prepared by the process of the invention inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.

Process For The Preparation Of Epothilone Analogs

US Patent:
RE39356, Oct 17, 2006
Filed:
Feb 11, 2005
Appl. No.:
11/056606
Inventors:
Wen Sen Li - Holmdel NJ, US
John E. Thornton - Newtown PA, US
Zhenrong Guo - East Brunswick NJ, US
Shankar Swaminathan - Monmouth Junction NJ, US
Robert M. Borzilleri - New Hope PA, US
Soong-Hoon Kim - Titusville NJ, US
Denis Favreau - St. Hubert, CA
Assignee:
Bristol-Myers Squibb Co. - Princeton NJ
International Classification:
C07D 491/00
C07D 417/00
US Classification:
540462, 548181, 548204
Abstract:
The present invention relates to a process for the preparation of epothilone analogs by initially forming novel ring-opened epothilones and carrying out a macrolactamization reaction thereon. The subject process is amenable to being carried out in a single reaction vessel without isolation of the intermediate compound and provides at least about a three-fold increase in yield over prior processes for preparing the desired epothilone analogs.

Process For The Preparation Of Epothilone Analogs

US Patent:
2003000, Jan 2, 2003
Filed:
Sep 5, 2001
Appl. No.:
09/946721
Inventors:
Wen Li - Holmdel NJ, US
John Thornton - Newtown PA, US
Zhenrong Guo - East Brunswick NJ, US
Shankar Swaminathan - Monmouth Junction NJ, US
International Classification:
C07D225/00
US Classification:
540/461000, 554/078000, 554/103000
Abstract:
The present invention relates to a process for the preparation of epothilone analogs by initially forming novel ring-opened epothilones and carrying out a macrolactamization reaction thereon. The subject process is amenable to being carried out in a single reaction vessel without isolation of the intermediate compound and provides at least about a three-fold increase in yield over prior processes for preparing the desired epothilone analogs.

Preparation Of [4S-(4.Alpha.,7.Alpha.,10A.beta.)]-4-Amino-Octahydro-5-Oxo-7H-Pyrido[2,1 -B] [1,3]Thiazepine-7-Carboxylic Acid, Methyl Ester And Salts Thereof Via Novel Disulfides

US Patent:
6162913, Dec 19, 2000
Filed:
Jul 8, 1999
Appl. No.:
9/349861
Inventors:
Jerome L. Moniot - Chester NJ
Sushil K. Srivastava - Dayton NJ
William J. Winter - Montgomery NY
John J. Venit - North Brunswick NJ
Shankar Swaminathan - North Brunswick NJ
Keith Ramig - Orange NJ
Paul A. Jass - Charles City IA
Mark D. Schwinden - Holland PA
John L. Dillon - East Syracuse NY
Saibaba Racha - East Syracuse NY
James Simpson - Belle Mead NJ
Chien-Kuang Chen - Marlboro NJ
Shawn K. Pack - Plainsboro NJ
Assignee:
Bristol-Myers Squibb Co. - Princeton NJ
International Classification:
C07D28102
C07C26100
C07C22904
C07C22922
US Classification:
540490
Abstract:
N-protected-L-homocysteine disulfide of the formula ##STR1## or an activated form thereof is reacted with (S)-2-amino-6,6-dimethoxyhexanoic acid, methyl ester to give the disulfide intermediate of the formula ##STR2## Cleavage of the disulfide bond followed by acid catalyzed cyclization produces the N-protected lactam of formula III which is useful for preparing the pharmaceutically active compound omapatrilat.

Enzymatic Oxidative Deamination Process

US Patent:
6261810, Jul 17, 2001
Filed:
Aug 31, 1999
Appl. No.:
9/386588
Inventors:
Ramesh N. Patel - Bridgewater NJ
Amit Banerjee - St. Louis MO
Venkata B. Nanduri - East Brunswick NJ
Laszlo J. Szarka - East Brunswick NJ
Shankar Swaminathan - North Brunswick NJ
John J. Venit - North Brunswick NJ
Jerome L. Moniot - Chester NJ
David A. Lust - Roosevelt NJ
Sushil K. Srivastava - Dayton NJ
Assignee:
Bristol-Myers Squibb Company
International Classification:
C12P 1718
US Classification:
435119
Abstract:
The present invention concerns an enzymatic oxidative deamination process of a dipeptide monomer to prepare an intermediate useful to prepare compounds having endopeptidase and angiotensin converting enzyme inhibition activity.

7-Oxabicycloheptane Carboxylic Acid Prostaglandin Analog Intermediates Useful In The Preparation Of Anti-Thrombotic And Anti-Vasospastic Compounds And Method For Preparing Same

US Patent:
H17370, Jun 2, 1998
Filed:
Mar 28, 1997
Appl. No.:
8/828460
Inventors:
Shankar Swaminathan - North Brunswick NJ
Philip M. Sher - Plainsboro NJ
Ambarish Singh - Bordentown NJ
Wen-Sen Li - Holmdel NJ
John J. Venit - North Brunswick NJ
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D26352
US Classification:
548217
Abstract:
A method is provided for preparing intermediates for 7-oxabicycloheptane carboxylic acid intermediates of the structures ##STR1## wherein R is alkyl, aryl, arylalkyl or cycloalkyl; R. sup. 1 is alkyl, arylalkyl or cycloalkyl; R. sup. 2 is aryl or arylalkyl; and of the structure ##STR2## where R and R. sup. 1 are as defined above, which may be used in making the final anti-thrombotic--anti-vasospastic compounds.

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