Hans G Noller1023 Redtail Rd, Norristown, PA 19403

5225351, Jul 6, 1993

Dec 17, 1990

7/628334

Hans G. Noller - Orange CA

Beckman Instruments, Inc. - Fullerton CA

G01N 100
G01N 2162

436172

In a method for reducing the latent low-level phosphorescence of laboratory glassware, the glassware is illuminated by infrared light with a wavelength of about 780 nanometers. A suitable infrared light source can be a xenon flash apparatus fitted with an infrared light filter. A single flash from the xenon apparatus can substantially reduce the latent low-level phosphorescence of laboratory glassware to a baseline phosphorescence level.

4857735, Aug 15, 1989

Oct 23, 1987

7/113230

Hans G. Noller - Orange CA

G01J 342

250339

A spectrophotometer incorporating a pulsed light emitting diode as a source of radiation. The light emitting diode emits substantially monochromatic light thus negating the need for a separate wavelength control. The spectrophotometer may incorporate a pair of light emitting diodes for performing bichromatic spectrophotometric determinations. The light emitting diodes are pulsed with a duty cycle and pulse amplitude such that it is possible to obtain a higher amplitude pulse than the light emitting diode could sustain at a continuous voltage input level. Continuous voltages at this level would damage the light emitting diode.

4668868, May 26, 1987

Feb 20, 1986

6/831324

Hans T. Noller - Philadelphia PA

G01N 2164

2504581

The output of a light source preferably of a fluorescent lamp is filtered to provide light energy in a predetermined spectrum and this light energy used to excite a biological specimen which may comprise antigens and antibodies which are tagged with flurorescent material. Light energy at a predetermined frequency is emitted by the fluorescent material in response to this excitation, the magnitude of this light energy representing the population of the biological specimen of interest. This light energy is used to excite a photovoltaic cell which produces an electrical output in accordance with the excitation thereof. Compensation for temperature drift and other offset voltages which might be developed in the photovoltaic cell is provided by means of a second mating photovoltaic cell from which light excitation is eliminated, the output of this second photovoltaic cell being used as a compensating bias voltage to eliminate voltage outputs due to temperature drift and other offset voltages. The output of the first photovoltaic cell is amplified and fed to an appropriate volt-meter for a readout indication. Compensation is also provided in the amplifier for drift correction by means of a push button calibrator which is used to provide a compensating bias voltage in accordance with the output of the photovoltaic cell with zero input signal which is memorized and then subtracted from the peak signal voltage detected from the fluorotagged specimen.