Ke Tony Xu, Age 45128 Lee Dr, West Concord, MA 01742

Ke Xu Phones & Addresses

128 Lee Dr, Concord, MA 01742

159 Kenrick St, Brighton, MA 02135 (617) 782-2788

Boston, MA

Cambridge, MA

91 Walnut St, Brookline, MA 02445

New York, NY

Amherst, MA

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Work

Company: Microsoft research asia Jan 2011 Position: Reserach intern

Education

School / High School: Worcester Polytechnic Institute- Worcester, MA Aug 2011 Specialities: Master of Science in Electronic Engineering

Ranks

Licence: New York - Currently registered Date: 2012

Mentions for Ke Tony Xu

Career records & work history

Lawyers & Attorneys

Ke Xu Photo 1

Ke Xu - Lawyer

Address:
Simmons & Simmons Beijing Representative Office
(106) 113-7564 (Office)
Licenses:
New York - Currently registered 2012
Education:
Vanderbilt University Law School
Ke Xu Photo 2

Ke Xu - Lawyer

ISLN:
924296900
Admitted:
2012

Medicine Doctors

Ke Xu Photo 3

Ke Tom Xu

Specialties:
Emergency Medicine

Resumes & CV records

Resumes

Ke Xu Photo 39

Ke Xu - Worcester, MA

Work:
Microsoft Research Asia Jan 2011 to Apr 2011
Reserach Intern
Beijing Greatwall Electrical Equipment LLC Aug 2010 to Dec 2010
Intern-Digital Circuit design
Research assistant Sep 2009 to Apr 2010
Education:
Worcester Polytechnic Institute - Worcester, MA Aug 2011
Master of Science in Electronic Engineering

Publications & IP owners

Us Patents

Location Based Data Delivery Schedulers

US Patent:
2013025, Oct 3, 2013
Filed:
Mar 30, 2012
Appl. No.:
13/436047
Inventors:
Philip Orlik - Cambridge MA, US
Ke Xu - Clemson SC, US
International Classification:
H04W 72/12
US Classification:
370337
Abstract:
Packets are transmitted by a server to mobile nodes in a coverage area of a wireless network using a coverage and reliability map, which indicates qualities and reliabilities of links between the server and the nodes. When a new packet is received in the server, the server transmits the packet if a current load of the packets including the new packet is less than a peak load constraint. Otherwise, the new packet is delayed for one time slot.

Compositions Of Exosomes And Aav

US Patent:
2022032, Oct 13, 2022
Filed:
Apr 17, 2020
Appl. No.:
17/594440
Inventors:
- Cambridge MA, US
Russell E. MCCONNELL - Cambridge MA, US
Ke XU - Belmont MA, US
Jonathan FINN - Cambridge MA, US
Assignee:
Codiak BioSciences, Inc. - Cambridge MA
International Classification:
A61K 35/761
A61K 47/42
A61K 47/64
A61K 9/00
A61P 27/02
A61P 3/10
C07K 14/005
C12N 15/86
Abstract:
The present disclosure relates to extracellular vesicles, e.g., exosomes, comprising an AAV and a scaffold protein. In some aspects, the AAV is in the lumen of the extracellular vesicle. In some aspects, the AAV is associated with the luminal surface of the extracellular vesicle. In some aspects, the AAV is associated with the exterior surface of the extracellular vesicle. Also provided herein are methods for producing the exosomes and methods for using the exosomes to treat and/or prevent diseases or disorders.

Extracellular Vesicles Targeting T Cells And Uses Thereof

US Patent:
2022025, Aug 11, 2022
Filed:
Jul 2, 2020
Appl. No.:
17/624524
Inventors:
- Cambridge MA, US
Kevin P. DOOLEY - Boston MA, US
Shelly Ann MARTIN - Stoneham MA, US
Ke XU - Belmont MA, US
Dalia BURZYN - Newton MA, US
Sriram SATHYANARAYANAN - Lexington MA, US
Joanne LIM - Natick MA, US
Assignee:
Codiak BioSciences, Inc. - Cambridge MA
International Classification:
C07K 16/28
C07K 14/705
Abstract:
The present disclosure relates to modified extracellular vesicles, e.g, exosomes, comprising a targeting moiety (e.g., anti-CD3 targeting moiety), wherein the targeting moiety can specifically bind to markers expressed on distinct immune cells (e.g., T cells). Also provided herein are methods for using the exosomes to treat and/or prevent a range of medical disorders.

Extracellular Vesicles For Treating Neurological Disorders

US Patent:
2023011, Apr 13, 2023
Filed:
Mar 15, 2021
Appl. No.:
17/906177
Inventors:
- Cambridge MA, US
Tim SOOS - Boston MA, US
Nikki ROSS - Philadelphia PA, US
Christine MCCOY - Cambridge MA, US
Jonathan FINN - Melrose MA, US
Sriram SATHYANARAYANAN - Lexington MA, US
Shailendra PATEL - Boston MA, US
Ke XU - Belmont MA, US
Russell E. MCCONNELL - Cambridge MA, US
Kevin P. DOOLEY - Boston MA, US
Assignee:
Codiak BioSciences, Inc. - Cambridge MA
International Classification:
A61K 39/00
A61P 25/28
A61K 39/39
A61P 35/00
A61K 31/436
A61K 31/593
A61K 31/203
A61K 31/573
A61K 31/7088
A61K 47/69
A61K 47/64
A61H 23/00
A61H 23/02
Abstract:
The present disclosure relates to extracellular vesicles (EVs) that are capable of targeting a cell in the CNS of a subject. Also provided herein are methods for producing the EVs and methods for using the EVs to treat and/or prevent diseases or disorders of the CNS (e.g., neurological disorders).

Exosomes For Immuno-Oncology And Anti-Inflammatory Therapy

US Patent:
2020040, Dec 31, 2020
Filed:
Jul 6, 2020
Appl. No.:
16/921351
Inventors:
- Cambridge MA, US
Yu ZHOU - Somerville MA, US
Sriram SATHYANARAYANAN - Lexington MA, US
John KULMAN - Belmont MA, US
Douglas E. WILLIAMS - Boston MA, US
Leonid A. GAYDUKOV - Tewksbury MA, US
Ke XU - Belmont MA, US
Shelly MARTIN - Stoneham MA, US
Assignee:
Codiak BioSciences, Inc. - Cambridge MA
International Classification:
C07K 14/715
C07K 14/705
C07K 16/28
C07K 14/54
C07K 14/475
C07K 14/57
C07K 14/52
C07K 14/47
Abstract:
Disclosed herein are extracellular vesicles comprising an immunomodulating component. Also provided are methods for producing the extracellular vesicles and methods for using the extracellular vesicles for treating cancer, GvHD, and autoimmune diseases.

Compositions Of Engineered Exosomes And Methods Of Loading Luminal Exosomes Pay-Loads

US Patent:
2020034, Nov 5, 2020
Filed:
Nov 16, 2018
Appl. No.:
16/765116
Inventors:
- Cambridge MA, US
Kevin P. DOOLEY - Boston MA, US
Rane A. HARRISON - Arlington MA, US
Ke XU - Belmont MA, US
Damian J. HOUDE - Plymouth MA, US
Sonya HAUPT - San Diego CA, US
John D. KULMAN - Belmont MA, US
Douglas E. WILLIAMS - Boston MA, US
Madeleine YOUNISS - Boston MA, US
Assignee:
Codiak BioSciences, Inc. - Cambridge MA
International Classification:
C07K 14/705
C12N 15/62
A61K 9/50
A61K 47/69
A61K 47/42
Abstract:
The present invention relates to methods of preparing a therapeutic exosome using proteins newly identified to be enriched in the lumen of exosomes. Specifically, the present invention provides methods of localizing a therapeutic peptide or protein in exosomes. The methods involve generation of lumen-engineered exosomes that include one or more of the exosome proteins at higher concentrations, a modification or a fragment of the exosome protein, or a fusion protein of the exosome protein and a therapeutic or cargo protein.

Preparation Of Therapeutic Exosomes Using Membrane Proteins

US Patent:
2020022, Jul 16, 2020
Filed:
Dec 20, 2019
Appl. No.:
16/722884
Inventors:
- Cambridge MA, US
Rane A. HARRISON - Belmont MA, US
Russell E. MCCONNELL - Brighton MA, US
Ke XU - Sudbury MA, US
Damian J. HOUDE - Plymouth MA, US
Nikki ROSS - Cambridge MA, US
Sonya HAUPT - Cambridge MA, US
John D. KULMAN - Belmont MA, US
Douglas E. WILLIAMS - Boston MA, US
Assignee:
Codiak BioSciences, Inc. - Cambridge MA
International Classification:
A61K 47/69
C07K 14/705
C07K 14/755
C07K 16/28
C07K 14/71
Abstract:
The present invention relates to methods of preparing a therapeutic exosome using a protein newly-identified to be enriched on the surface of exosomes. Specifically, the present invention provides methods of using the proteins for affinity purification of exosomes. It also provides methods of localizing a therapeutic peptide on exosomes, and targeting exosomes to a specific organ, tissue or cell by using the proteins. The methods involve generation of surface-engineered exosomes that include one or more of the exosome proteins at higher density, or a variant or a fragment of the exosome protein.

Exosomes For Immuno-Oncology And Anti-Inflammatory Therapy

US Patent:
2019020, Jul 4, 2019
Filed:
Dec 28, 2018
Appl. No.:
16/236246
Inventors:
- Cambridge MA, US
Yu Zhou - Somerville MA, US
Sriram Sathyanarayanan - Lexington MA, US
John D. Kulman - Belmont MA, US
Douglas E. Williams - Boston MA, US
Leonid A. Gaydukov - Malden MA, US
Ke Xu - Sudbury MA, US
Shelly Martin - Stoneham MA, US
International Classification:
C07K 14/715
C07K 14/705
Abstract:
Disclosed herein are extracellular vesicles comprising an immunomodulating component. Also provided are methods for producing the extracellular vesicles and methods for using the extracellular vesicles for treating cancer, GvHD, and autoimmune diseases.

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