Yajun Xu resumes & CV records
Resumes
Yajun Xu
Yajun J Xu, Age 60Las Vegas, NV
Yajun Xu Phones & Addresses
Las Vegas, NV
San Marcos, CA
Woburn, MA
49 Amherst Rd, Belmont, MA 02478 (617) 229-9606
Allston, MA
Acton, MA
Harvard, MA
Westborough, MA
Lexington, MA
Waltham, MA
49 Amherst Rd, Belmont, MA 02478
Mentions for Yajun J Xu
Publications & IP owners
Us Patents
Indeno[1,2-C]Pyrazole Derivatives For Inhibiting Tyrosine Kinase Activity
US Patent:
6534655, Mar 18, 2003
Filed:
Apr 3, 2000
Appl. No.:
09/541309
Inventors:
Lee D. Arnold - Westborough MA
Yajun Xu - Westborough MA
Teresa Barlozzari - Wellesley MA
Paul Rafferty - Nottingham, GB
Michael Hockley - Nottingham, GB
Allyson Turner - Nottingham, GB
Yajun Xu - Westborough MA
Teresa Barlozzari - Wellesley MA
Paul Rafferty - Nottingham, GB
Michael Hockley - Nottingham, GB
Allyson Turner - Nottingham, GB
Assignee:
BASF Aktiengesellschaft - Ludwigshafen
International Classification:
C07D40104
US Classification:
5462757, 514338, 514339, 5483591
Abstract:
Chemical compounds that are derivatives of indeno[1,2-c]pyrazole are inhibitors of tyrosine kinase activity. Several of the tyrosine kinases, whose activity is inhibited by these chemical compounds, are involved in angiogenic processes. Thus, these chemical compounds can ameliorate disease states where angiogenesis or endothelial cell proliferation is a factor. Compounds of this invention also inhibit the induction of vascular hyperpermeability and the associated formation of edema, ascites, and exudates.
Indeno[1,2-C]-, Naphtho[1,2-C]- And Benzo[6,7]Cyclohepta[1,2-C]Pyrazole Derivatives
US Patent:
6451834, Sep 17, 2002
Filed:
Apr 3, 2000
Appl. No.:
09/541222
Inventors:
Lee D. Arnold - Westborough MA
Yajun Xu - Westborough MA
Teresa Barlozzari - Wellesley MA
Yajun Xu - Westborough MA
Teresa Barlozzari - Wellesley MA
Assignee:
BASF Aktiengesellschaft - Ludwigshafen
International Classification:
A61K 31415
US Classification:
514406, 514403, 514438, 514461
Abstract:
Chemical compounds that are derivatives of indeno[1,2-c]-, naphtho[1,2-c]- and benzo[6,7]cyclohepta[1,2-c]pyrazole are inhibitors of tyrosine kinase activity. Several of the tyrosine kinases, whose activity is inhibited by these chemical compounds, are involved in hyperproliferative, angiogenic or in vascular hyperpermeability processes. Thus, these chemical compounds can ameliorate disease states where tumor formation, metastasis, angiogenesis, vascular hyperpermeability or endothelial cell proliferation is a factor.
Possible Relatives
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